Otsuka Pharmaceutical Company, Limited

Kouichi Tsuji

Setsuro Fujii

Hiroshi Ishikawa

Hidetsugu Tsubouchi

Koichi Yasumura

Kimio Sudo

Koichiro Jitsukawa

Sachio Toyama

A 2-oxa-isocephem compound of the formula (1): ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined, pharmaceutically acceptable salts thereof, composition containing the same and processes for preparing the same are disclosed. The compound is useful as an antimicrobial agent.

2-oxa-isocephem compounds

2-Oxa-isocephem compounds and compositions containing same

A 2-oxa-isocephem compound of the formula (1): ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are as defined, pharmaceutically acceptable salts thereof, esters of the carboxy group in the 4-position thereof and quaternary ammonium salts thereof, composition containing the same and processes for preparing the same are disclosed. The compound is useful as an antimicrobial compound.

2-oxa-isocephem compounds, compositions containing same and processes of

Growing community of inventors

Otsu, Japan

Kouichi Tsuji