Takeda Pharmaceutical Company Limited

Matsushita Electric Works, Ltd.

Kouichi Iwanaga

Satoshi Yamamoto

Hidekazu Tokuhara

Takanobu Kuroita

Yasuhiro Imaeda

Naohiro Taya

Shinji Nakamura

Norihito Tokunaga

Satoshi Mikami

Shinji Morimoto

Minoru Nakamura

Masaki Seto

Makoto Kamata

Kazuaki Takami

Yuya Oguro

Shigemitsu Matsumoto

Masaki Daini

Masataka Murakami

Mitsuhiro Ito

Taku Kamei

Jumpei Aida

Takeshi Wakabayashi

Yasufumi Wada

Taisuke Tawaraishi

Sachie Takashima

Hiroyuki Kakei

Toshihiro Imaeda

Shoji Fukumoto

Yoshiyuki Fukase

Yasutomi Asano

Masakuni Kori

Koichiro Fukuda

Osamu Ujikawa

Masakatsu Araki

Hideaki Haraguchi

Hikoyoshi Hara

Hiromi Kakumoto

Hiroshi Kikuchi

Masami Kitamura

Katsuji Nakamura

Shinichirou Tsujimura

Sataro Nasu

Sataroh Nasu

The present invention provides a heterocyclic compound having an antagonistic action on an NMDA receptor containing the NR2B subunit, and expected to be useful as an agent for the prophylaxis or treatment of major depression, bipolar disorder, migraine, pain, behavioral and psychological symptoms of dementia and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.

Heterocyclic compound and use thereof

Provided is a compound having an AMPA receptor function enhancing action, and useful as a prophylactic or therapeutic drug for depression, Alzheimer's disease, schizophrenia, attention deficit hyperactivity disorder (ADHD) and the like. A compound represented by the formula (I): wherein each symbol is as defined in the present specification,or a salt thereof.

Sulfonamide derivative and use thereof

Compounds represented by the formulas wherein each symbol is as defined in the specification, and a prodrug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.

Compounds represented by the formulas (I) (II) wherein each symbol is as defined in the specification, and a prodrug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like. 

A battery pack containing a rechargeable battery is detachable to a charger unit for charging under the control of a charging circuit in the charger unit. The battery pack includes a sensor output circuit which comprises a temperature sensor for sensing the temperature of the battery being charged. A voltage dividing resistor network is formed in the sensor output circuit and receives a constant current from the charging circuit upon attachment of the battery pack to the charger unit such that it provides an enable signal of a first voltage level to the charging circuit for allowing the charging of the battery at a first charge rate so long as the sensed battery temperature is below a predetermined reference level. When the sensed battery temperature exceeds the reference level, the voltage dividing resistor network responds to provide a stop signal of a second voltage level for inhibiting the charging at the first charge rate. Also included in the sensor output circuit is a hold circuit which holds to provide the stop signal to the charging circuit once the sensed temperature exceeds the reference level.

Rechargeable battery pack and charger unit combination

A hair clipper has cutter head comprising a set of a stationary blade and a movable blade each having teeth in its forward edge. The movable blade is driven to reciprocate on the stationary blade for hair shearing. The hair shearing can be operated selectively at either of hair cutting, hair trimming, and hair thinning modes which are characterized to have respective effective hear shearing zones of different capability optimum suitable for the intended modes.

Hair clipper

A casing for an electric appliance provided on its outer surface with a plurality of minute tapered projections which are of 15 to 30 microns in height and bottom diameter whereby a minute projections shed the water wetting the body resulting in the water not having a bad effect upon the electric appliance.

Casing of a washable electric appliance

Electric shaver of battery powered and washable type having a watertight housing structure. A battery covering detachably mounted to housing bottom opening for holding batteries inside the housing includes a lock and seal which are activated, responsive to the covering's mounting operation, respectively in directions transversing the housing axis to lock the covering to the housing interior wall and in the housing axial directions to achieve uniform abuttment of the covering to the interior wall for clamping therebetween a watertight ring seal. At the housing head where shaving blade assembly is coupled to rotary shaft of electric motor, the shaft is projected out of an axial cylinder of motor mounting member through a double-lip shape bushing watertightly sealing around the shaft with both axial end and outer peripheral projections compressively deformed by inward flange and inner periphery of the axial cylinder and motor shaft bearing so as to maintain a proper sealing pressure about the shaft, while allowing water passed through cut-hair reservoir between the motor and the blade assembly with side wall apertures of the reservoir closable by a shutter ring slidably fitted therearound, and in a housing side wall a reed-switch inside the housing is controlled over the side wall by a magnet carried by a handle slidably fitted outside the wall.

Electric shaver

Battery charging device having a function of indicating in sounds at least one of charging and discharging states of a storage battery, specifically adapted to be incorporated in battery operated electric implements. During charge operation, a charging circuit oscillatorily generates from a rectified direct current of commercial AC source current a high frequency charging voltage, of which oscillation becomes intermittent with varying intervals after a predetermined battery charge level is reached, whereby a charge complete detecting circuit causes a sound generating device to be operated to sound discriminatively initial and final charge complete indications responsive to the varying intervals. During discharge operation, a charge remind detecting circuit provides an output to the sound generating means only after a predetermined discharge level is reached, to cause the means device to be operated to sound a charge remind indication.

Battery charging device having battery state indicating function

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Osaka, Japan

Kouichi Iwanaga