Hokkaido System Science Co., Ltd.

Osaka University

Daiichi Sankyo Company, Limited

National Cerebral and Cardiovascular Center

Kouichi Hashimoto

Hideo Kobayashi

Hiroshi Kikuchi

Daigo Asano

Ayako Iijima

Masatsugu Hori

Masafumi Kitakaze

Tetsuo Minamino

Junko Yasuda

Hiroyuki Takahama

The present invention relates to a novel preventive and/or therapeutic drug for myocardial infarction. The present invention provides a preventive and/or therapeutic drug for myocardial infarction or myocardial ischemia-reperfusion injury, the drug containing a lipid membrane structure retaining adenosine.

Prophylactic and/or therapeutic agent for cardiac infarction

The invention provides a nucleic-acid-transfecting composition which exhibits low cytotoxicity, which facilitates an effective nucleic acid transfection into a cell, and which improves expression of the nucleic acid in the cell. The composition for transfecting a nucleic acid into a cell, contains a di(Calkyl)dimethylammonium halide and a phospholipid.

Composition for nucleic acid transfection

To provide a nucleic-acid-transfecting composition which exhibits low cytotoxicity, which facilitates a nucleic acid transfection into cells, and which improves expression of the nucleic acid in the cells. The invention provides a composition for transfecting a nucleic acid into a cell, including a compound represented by the following formula (I) (wherein each of Rand R, which are identical to or different from each other, represents a saturated or unsaturated hydrocarbon group; Rrepresents a Calkyl group or a Chydroxyalkyl group; m is an integer from 1 to 10; and X represents a halogen atom), and a phospholipid. 

Composition for nucleic-acid transfection

Growing community of inventors

Yachiyo, Japan

Kouichi Hashimoto