Nissan Chemical Industries Limited

Kotatsu Matsubara

Masaki Kobayashi

Takeshi Mita

Kunimitsu Nakahira

Hotaka Imanaka

Kazutaka Matoba

Rika Miyachi

Masashi Ohno

Takahiro Kagami

A method for manufacturing a crystal and a crystal of (S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide and a method for manufacturing the crystal. It is elucidated that (S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide that has a crystalline polymorph.

Crystalline polymorphs of isoxazoline compound and production method thereof

Growing community of inventors

Funabashi, Japan

Kotatsu Matsubara