Nihon Medi-Physics Company, Limited

National Institutes for Quantum Science and Technology

Kotaro Nagatsu

Jun Ichinose

Taku Ito

Yoshio Honda

Hiroaki Ichikawa

Hisashi Suzuki

Tomoyuki Imai

A method for producing anAc solution includes a step (I) of irradiating aRa target with particles to generate two or more actinium radioisotopes (Ac) including at leastAc, a step (II) of dissolving theRa target after the aforementioned step to obtain a solution (1), a step (III) of separatingRa and Ac contained in the solution (1) to obtain a solution (2), a step (IV) of allowing Ac contained in the solution (2) other thanAc to decay to obtain a solution (3), and a step (V) of separating Ra and Ac contained in the solution (3) to obtain a solution (4). The solution (4) is used to produce a medicine that contains, as an active ingredient, a conjugate between a chelating agent that has formed a complex withAc, and a targeting agent.

Method for producing Ac-225 solution and method for producing medicine using Ac-225 solution

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Chiba, Japan

Kotaro Nagatsu