Shimadzu Corporation

Kota Kamei

Daisuke Kitabayashi

A liquid chromatograph () includes a liquid-sending unit () for sending a mobile phase from a reservoir () to a column () through a tube () at a predetermined pressure. The unit () includes a pump () having a suction port () connected to the reservoir and an ejection port () connected to the tube directly or via another pump. A check valve () is provided for the ejection port. For the precompression process for opening this valve, a pressure application controller () controls the pressure applied to the mobile phase within the pump, based on the compressibility of the mobile phase and the amount of compression of the inner wall of the pump resulting from the pressure application, so as to reach the pressure at which the check valve opens before the mobile phase suctioned from the suction port is to be ejected from the ejection port.

Liquid chromatograph

A gas sample introduction device includes a sample container connection flow path, a sample loop and a first flow path switching valve, having a first state in which the pressurizing gas is supplied to the sample container connection flow path via the sample loop and a second state in which the pressurizing gas is supplied to the sample container connection flow path without via the sample loop. A leak check method includes a first determination step of determining whether or not there is a gas leak by setting the first flow path switching valve to a first state and a second determination step of identifying a location of a gas leak by performing a second determination of whether or not there is a gas leak by setting the first flow path switching valve to a second state, when there is a gas leak in the first determination step.

Growing community of inventors

Kyoto, Japan

Kota Kamei