Koninklijke Philips Corporation N.V.

Kostyantyn Volyanskyy

Nevenka Dimitrova

Larry James Eshelman

Minnan Xu

Yong Mao

In a risk level assessment method for a plurality of clinical conditions as follows, a set of laboratory test results () are stored with time stamps for a patient, including at least one hematology test result and at least one arterial blood gas (ABG) test result. For each clinical condition, a risk level is determined for the clinical condition based on a clinical condition-specific sub-set of the stored set of laboratory test results. This determination is made conditional on the stored clinical condition-specific sub-set of laboratory test results being sufficient to determine the risk level. A time stamp is assigned to each determined risk level based on the time stamps for the laboratory test results of the clinical condition-specific sub-set of laboratory test results. A display device () displays the determined risk level and the assigned time stamp for each clinical condition whose determined risk level satisfies a display criterion.

System for laboratory values automated analysis and risk notification in intensive care unit

The present disclosure pertains to a system, a method of using such a system, and a non-transitory computer-readable medium containing instructions to such a system for generating annotated gene fusion data from processing both a patient's DNA and RNA sequence information thereby filtering out weak candidate gene fusions. Thus the annotated gene fusion data contains clinically relevant information and accurate gene fusion detections (low false-positives) for use in clinical and/or R&D settings. The system, method and computer-readable medium allows a user to generate gene fusion data by detecting breakpoints from a patient's DNA-SEQ and RNA-SEQ, creating candidate breakpoint data by combining matching breakpoints from the DNA-SEQ and RNA-SEQ breakpoint data, determining confidence levels of the candidate breakpoint, identifying corresponding gene fusions, and annotating clinically relevant information about the gene fusions.

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Larchmont, NY, United States of America

Kostyantyn Volyanskyy