Northeastern University

Kostas Papamarkakis

Max Diem

Benjamin Bird

Milos Miljkovic

Melissa Romeo

Jennifer Schubert

Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell.

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Springfield, MA, United States of America

Kostas Papamarkakis