Nippon Kayaku Kabushiki Kaisha

Kooichi Yoshida

Hiroshi Ninomiya

Katsutoshi Takahashi

Osamu Yoshioka

Akira Matsuda

Yukio Aoda

Osamu Koyanagi

Disclosed is a pharmaceutical vehicle comprising (a) a fatty acid glyceride having a melting point higher than 37.degree. C., (b) a water-soluble, low viscous and non-irritating organic substance having a particle size smaller than 28 mesh and a viscosity lower than 300 cps as measured with respect to a 2% aqueous solution, (c) an organic polymeric substance having a particle size smaller than 28 mesh, which is capable of being swollen on contact with water, and (d) a water-soluble surface active agent.

Pharmaceutical vehicle

This invention relates to a method for selectively enhancing absorption of 5-fluorouracil, bleomycins or bleomycin derivatives into the gastrointestinal tumor site by orally administering such substance together with an alkali metal salt of polyacrylic acid, and an orally administrable antitumor composition used for such method.

Method of enhancing absorption of antitumor agent into gastro-intestinal

This invention relates to a method for selectively enhancing absorption of 5-fluorouracil, bleomycins or bleomycin derivatives into the gastrointestinal tumor site by orally administering such substance together with an alkali metal salt of polyacrylic acid, and an orally administable antitumor composition used for such method.

Growing community of inventors

Soka, Japan

Kooichi Yoshida