Tufts College

Boston University

Tufts University

Konstantinos Tsioris

Fiorenzo G Omenetto

David L Kaplan

Eleanor M Pritchard

Xin Zhang

Richard Douglas Averitt

Hu Tao

Andrew Strikwerda

A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery.

Silk fibroin-based microneedles and methods of making the same

The invention relates to silk electronic components and methods for fabricating the same. The silk electronic components can be used as novel devices, such as implantable bioelectric and/or biophotonic devices, biosensors, surveillance devices, invisible cloaks, electromagnetic concentrators or antennas.

Silk electronic components

Growing community of inventors

Somerville, MA, United States of America

Konstantinos Tsioris