The University of Texas System

Konstantin Sokolov

Rebecca Rae Richards-Kortum

Urs Utzinger

Jignesh M Shah

Stanislav Emelianov

Rebekah A Drezek

Wolfgang Frey

Bo Wang

Jimmy Su

Yun-Sheng Chen

The present disclosure relates to methods and systems relating to temperature dependent photoacoustic imaging are provided. In such methods and systems, a tissue sample may be exposed to thermal energy and electromagnetic radiation to generate an acoustic signal, which may be detected. The amplitude of the acoustic signal may be determined and correlated with a tissue property, such as the presence or absence of macrophages or foam cells.

Temperature dependent photoacoustic imaging

Methods and apparatus for assessing the size of a scattering element of a sample. Primary radiation is generated from a source. The primary radiation is polarized to produce polarized primary radiation. The polarized primary radiation is directed to the sample to generate reflected radiation. The reflected radiation is directed through a polarizer to produce filtered reflected radiation, the polarizer being configured to select reflected radiation parallel and perpendicular to the polarization of the polarized primary radiation. The filtered radiation is detected, and a depolarization ratio is calculated using the detected filtered radiation. The size of the scattering element is calculated using the depolarization ratio.

Methods and apparatus for polarized reflectance spectroscopy

Growing community of inventors

Austin, TX, United States of America

Konstantin Sokolov