Morinaga Milk Industry Co., Ltd.

Sony Corporation

Koji Yamauchi

Mitsunori Takase

Mamoru Tomita

Hiroyuki Wakabayashi

Seiichi Shimamura

Yoshitaka Tamura

Wayne R Bellamy

Kozo Kawase

Kouichirou Shin

Hitoshi Saito

Susumu Kobayashi

Hiroshi Miyakawa

Yasuo Fukuwatari

Kimiyasu Shiraki

Hiroaki Abe

Masahiko Kurokawa

Kouzou Kawase

Yukiko Tokita

Kanetada Shimizu

Yasuhiro Takeda

Ayako Horigome

Mai Murata

Junichi Hashimoto

Nobuo Ichihashi

Takumi Sato

Tetsuya Ando

Ikumi Kojima

Masaki Yoshimura

Hirotsugu Oda

Yukio Tokita

Yukiko Tokida

Kouzo Kawase

A peptide dimer comprising a peptide consisting of the amino acid sequence of SEQ ID NO: 1 and a peptide consisting of any one of the amino acid sequences of SEQ ID NOS: 2 to 4, wherein the peptide consisting of the amino acid sequence of SEQ ID NO: 1 and the peptide consisting of any one of the amino acid sequences of SEQ ID NOS: 2 to 4 are bound through a disulfide bond between a cysteine residue of each peptide is used as an active ingredient of an agent for promoting proliferation of one or more bacterium selected from the group consisting ofand

Agent for promoting proliferation of bifidobacteria

An audio visual system includes an input unit for receiving data containing video data and audio data and dividing the data into the audio data and the video data, a video decoder for decoding the video data divided by the input unit, an audio decoder for decoding the audio data divided by the input unit, and an output unit for superimposing and outputting the video data decoded by the video decoder and the audio data decoded by the audio decoder. The video decoder or audio decoder has a plurality of data output paths and sets delay times for each of the output paths to synchronize the decoded video data with the decoded audio data.

Audio visual system and decoder therefor

An agent for thermally stabilizing lactoferrin, which comprises a nucleic acid as an active ingredient, can be added to lactoferrin to impart thermal stability to lactoferrin. Thermally stabilized lactoferrin can be heat-sterilized at a pH value around a neutral pH value while keeping its activity.

Method of imparting heat resistance to lactoferrin

A process for producing lactoperoxidase, including: a step (1) for bringing one or more milk materials into contact with a cation exchanger having weakly acidic groups as ion exchange groups to thereby effect adsorption treatment; a step (2) for washing the cation exchanger after the adsorption treatment; a step (3) for bringing the cation exchanger after the washing into contact with a leaching solvent to thereby obtain a leaching solution having lactoperoxidase eluted into the leaching solvent; a step (4) for concentrating the leaching solution through an ultrafiltration membrane to thereby effect precipitation in the concentrated leaching solution; and a step (5) for obtaining a lactoperoxidase solution by removing the precipitation from the concentrated leaching solution.

Process for producing lactoperoxidase

An interleukin-6 suppressive agent comprising lactoperoxidase as an active ingredient is used as a pharmaceutical preparation or the like for prevention and/or therapy of a disease caused by production of interleukin-6, such as thrombocytosis, myeloma, Castleman syndrome, rheumatoid arthritis, or influenza-virus infectious disease.

Interleukin-6 suppressive agent

Antioxidant

Antimicrobial agents and method for treating products therewith

An antimicrobial peptide containing at least the following amino acid sequence, or a derivative thereof, an antimicrobial agent containing said antimicrobial peptide or a derivative thereof as active components at a concentration of at least 1 .mu.M, an antimicrobial composition containing said antimicrobial peptide or a derivative thereof, and a method for processing products which uses the antimicrobial agent containing at least said antimicrobial peptide or a derivative thereof:

Antimicrobial peptide and antimicrobial agent

An antimicrobial peptide containing an amino acid sequence comprising at least from three to six arbitrary amino acid residues, or a derivative thereof, an antimicrobial agent containing said antimicrobial peptide or a derivative thereof as active components at a concentration of at least 2 .mu.M, an antimicrobial composition containing said antimicrobial peptide or a derivative thereof, and a method for processing products which uses the antimicrobial agent containing at least said antimicrobial peptide or a derivative thereof.

Lactoferrin hydrolyzates, having a decomposition rate between 6%-20% as measured by formol titration, for use as an antibacterial agent, and which have remarkably more potent activity than unhydrolyzed lactoferrin; and lactoferrin hydrolyzates, having a decomposition rate between 4-50% as measured by formol titration, for use as a tyrosinase inhibition agent, are obtainable by conventional methods for hydrolysis with acids or enzymes, and are stable to heating.

Lactoferrin hydrolyzate for use as an antibacterial agent and as a

Lactoferrin hydrolyzates, having a decomposition rate between 6%-20% as measured by formol titration, for use as an antibacterial agent and which have remarkly more potent activity than unhydrolyzed lactoferrin; and lactoferrin hydrolyzates, having a decomposition rate between 4-50% as measured by formol titration, for use as a tyrosinase inhibition agent, are obtainable by conventional methods for hydrolysis with acids or enzymes, and are stable to heating.

Growing community of inventors

Zama, Japan

Koji Yamauchi