Snow Brand Milk Products Co., Ltd.

Koji Tamura

Makoto Yoshihama

Masamichi Nakakoshi

Nobuo Miyata

Shoji Nakayama

Novel 7.beta.-hydroxy-4-pregnene-3,20-dione derivatives are disclosed. The group of these compounds has possibility of being utilized as an intermediate for the synthesis of progesterone derivatives having ovulation-inhibiting activity. These compounds themselves have also cell differentiation activity for M1 cells.

Method for preparing 7.beta.-hydroxy-4-pregnene-3,20-dione derivatives

Novel androst-4-ene-3,17-dione derivatives are disclosed. The group of these compounds has biological activities, in particular, the inhibiting activity on human placenta-derived estrogen-synthesizing enzyme. Therefore these compounds are expected to be utilized in the field of medical care, particularly as anticancer drugs.

Growing community of inventors

Shimotsuga, Japan

Koji Tamura