Sony Corporation

Daiichi Sankyo Company, Limited

Mitsubishi-kagaku Foods Corporation

Mitsubishi Electric Corporation

Sankyo Company, Limited

Meinan Machinery Works, Inc.

Mitsubishi Denki Kabushiki Kaisha

Kao Corporation

Resonac Corporation

Nippon Steel Corporation

Z. I. Nekrasov Iron & Steel Institute of the National Academy of Sciences of Ukraine

Koji Morita

Hideki Miyazaki

Takeshi Masuda

Hiroyuki Naito

Yosuke Hosoya

Masao Yoshida

Yuji Kasuya

Takashi Nakada

Shinji Ashida

Yuki Abe

Yusuke Ogitani

Haruo Watanabe

Tomoyo Ooyama

Hideto Azuma

Guohua Li

Masakatsu Kaneko

Takeshi Imanishi

Shunsuke Saito

Masayuki Ihara

Makoto Koizumi

Hiroyuki Yamaguchi

Kenji Ogisu

Masanori Soma

Ichiro Hayakawa

Takao Mogi

Hideki Nakai

Hisao Okada

Kazunari Motohashi

Kotaro Satori

Tadahiko Kubota

Shigeru Fujita

Tomio Iwasaki

Kunihiko Hayashi

Takehiko Ishii

Yoshikazu Kato

Yoshihiro Kudo

Ichiro Yamada

Takehiko Toh

Satoshi Fujiki

Nozomu Morita

Kazuaki Endoh

Kiyohiko Suzuki

Tadashi Matsushita

Shuhei Sugita

Yoshimasa Okamoto

Hiroto Tanamachi

Shinichi Katayama

Hisashi Tsujimoto

Hirokazu Sakai

Takashi Ono

Kenichiro Naito

Nobuya Okano

Chihiro Hayashi

Noritoshi Araki

Ryo Kuya

Minoru Umetsu

Miho Sato

Keiichi Kasuga

Toshiyuki Takase

Michitaka Matsuo

Kana Wato

Naoto Sasaki

Kazuki Hibino

Ryo Shimokawa

Shinji Tsuchikawa

Muneaki Ando

Hiroshi Hirata

Masamitsu Wakoh

Yiguo Yan

Kazuo Onuki

Sohichi Niino

S I Semykin

As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L-L-L-NH—(CH)n-L-L-L- wherein the antibody is connected to the terminal of L, and the antitumor compound is connected to the terminal of Lwith the nitrogen atom of the amino group at position 1 as a connecting position.

Antibody-drug conjugate

A thermosetting resin composition containing a maleimide compound (a) having at least one N-substituted maleimide group, and a compound (b) represented by the following general formula (1) exhibiting no reactivity with the maleimide group of the component (a) (Xrepresents a single bond or a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 5 carbon atoms; Rand Reach independently represent a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 10 carbon atoms, a substituted or unsubstituted aromatic hydrocarbon group having 6 to 18 ring carbon atoms, a substituted or unsubstituted heterocyclic aromatic hydrocarbon group having 5 to 20 ring atoms, an oxygen atom-containing group, or a group containing a combination of these groups; and m and n each independently represent an integer of 0 to 5).

Thermosetting resin composition, prepreg, laminate, metal-clad laminate, printed wiring board, and high-speed communication compatible module

Provided is a veneer sorting control device including: a sorting condition setting unitthat sets sorting conditions for each of a plurality of kinds of defects so as to sort a veneer into a plurality of quality ranks; a defect detection unitthat detects the plurality of kinds of defects with respect to each of a plurality of pieces of veneer image data acquired from an image storage unit; a quality rank sorting unitthat sorts a plurality of the veneers into a plurality of quality ranks in correspondence with the sorting conditions which are set and defect detection states; a first totalization unitthat totalizes the number or a number ratio of the veneers in the plurality of quality ranks which are sorted; and a display control unitthat displays the totalization result on a screen. The number of the veneers sorted into the plurality of quality ranks can be confirmed by a simulation using the veneer image data stored in the image storage unit

Veneer sorting control device, veneer sorting control method, and program for veneer sorting control

As an antitumor drug which is excellent in terms of antitumor effect and safety and has an excellent therapeutic effect, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-HER2 antibody via a linker having a structure represented by the following formula: -L-L-L-NH&#x2014;(CH)n-L-(CH)n-C(&#x2550;O)&#x2014; wherein the anti-HER2 antibody is connected to the terminal L, and the antitumor compound is connected to the carbonyl group of the &#x2014;(CH)n-C(&#x2550;O)&#x2014; moiety with the nitrogen atom of the amino group at position 1 as the connecting position

Method for treating cancer comprising administration of anti-HER2 antibody-drug conjugate

As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L-L-L-NH&#x2014;(CH)n-L-L-L- wherein the antibody is connected to the terminal of L, and the antitumor compound is connected to the terminal of Lwith the nitrogen atom of the amino group at position 1 as a connecting position.

A lightfor reflected light that emits visible light for reflected light onto a front side of a veneer, a lightfor invisible light that emits near-infrared light for transmitted light onto a back side of the veneer, and an image processing devicethat detects defects of the veneerby analyzing a captured image generated by a line sensor cameraare provided. Defects of the veneerare discriminated on the basis of a set of shading and shapes in an infrared-transmitted-light image based on the transmitted light, and colors in a visible-light image based on the reflected light. Consequently, even if a defect has a small color difference from a normal part in the visible-light image, difference of shading between the defective part and the normal part appears in the infrared-transmitted-light image, and a defect that is difficult to detect by seeing only a color difference in a visible-light image can be relatively easily detected.

Defect inspection system, defect inspection method, and defect inspection program for wood plank

As an antitumor drug which is excellent in terms of antitumor effect and safety and has an excellent therapeutic effect, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-HER2 antibody via a linker having a structure represented by the following formula: -L-L-L-NH&#x2014;(CH)n-L-(CH)n-C(&#x2550;O)&#x2014; wherein the anti-HER2 antibody is connected to the terminal L, and the antitumor compound is connected to the carbonyl group of the &#x2014;(CH)n-C(&#x2550;O)&#x2014; moiety with the nitrogen atom of the amino group at position 1 as the connecting position. 

Method of treating cancer comprising administration of anti-HER2 antibody-drug conjugate

A program display control unit performs a display process of displaying first time-series data corresponding to a specified time specified by a display time specification unit, on a first sequence program stored in a first device, which is displayed in a second display section, and another display process of displaying second time-series data acquired from a second device of multiple devices, corresponding to the specified time specified by the display time specification unit, on a second sequence program stored in the second device, which is displayed in a third display section.

Device state reproduction device, device state reproduction method, and storage medium

As an antitumor drug which is excellent in terms of antitumor effect and safety and has an excellent therapeutic effect, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-HER2 antibody via a linker having a structure represented by the formula: L-L-L-NH&#x2014;(CH)n-L-L-Lor -L-L-L- wherein the anti-HER2 antibody is connected to the terminal L, and the antitumor compound is connected to the terminal Lor Lwith the nitrogen atom of the amino group at position 1 as the connecting position. 

(Anti-HER2 antibody)-drug conjugate

An information processing device includes a communication processing unit that performs communication with an external device according to an instruction from application software, and a trace processing unit that executes a first information trace process when a first predetermined condition is satisfied and executes a second information trace process when a second predetermined condition is satisfied. The first information trace process includes obtaining, from an operating system, environmental information that is information about an operating environment of the application software and writing the environmental information to an environmental information log file. The second information trace process includes writing, to a communication log file, information indicating a procedure of communication that the communication processing unit performs with the external device, obtaining the environmental information from the operating system, and writing the environmental information to the environmental information log file.

Information processing device, information processing method, and computer readable medium for a trace process

As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula:-L-L-L-NH&#x2014;(CH)-L-L-L-wherein the antibody is connected to the terminal of L, and the antitumor compound is connected to the terminal of Lwith the nitrogen atom of the amino group at position 1 as a connecting position.

Anti-HER2 antibody-drug conjugate

A battery is composed of a positive electrode in which a positive electrode active material layer including a positive electrode active material is formed on a positive electrode collector, a negative electrode in which a negative electrode active material layer including a negative electrode active material is formed on a negative electrode collector, a separator provided between the positive electrode and the negative electrode, and an electrolyte impregnated in the separator. The battery further includes at least one of a heteropoly acid and a heteropoly acid compound as an additive at least in one of the positive electrode, the negative electrode, the separator, and the electrolyte.

Non-aqueous electrolyte battery including an amorphous material

Growing community of inventors

Tokyo, Japan

Koji Morita