Kabushiki Kaisha Yakult Honsha

Konica Minolta, Inc.

Otsuka Pharmaceutical Company, Limited

Riken Corporation

Konica-minolta Holdings, Inc.

Konica Minolta Medical and Graphic, Inc.

Lintec Corporation

Kyushu University

Kyushu Institute of Technology

Tokyo Metropolitan Institute for Geriatrics and Gerontology

Koji Miyazaki

Satoshi Yoshikawa

Hideyuki Fujii

Yoshio Hiraki

Hiroshi Endo

Shoji Yamamoto

Koichi Watanabe

Masayuki Kimura

Akihisa Nakajima

Satoshi Wada

Noriaki Yamamoto

Youichi Aoki

Tetsuya Noda

Satoshi Matsubara

Shinichi Imai

Toshiro Sone

Takanori Murayama

Atsuo Iwashita

Teruaki Hayakawa

Kou Osawa

Tomoyuki Sako

Katsuyoshi Chiba

Junji Fujimoto

Yasuhisa Shimakawa

Jungo Araki

Mika Miura

Tomoko Hanamizu

Tsuneko Chiyoda

Takayo Ogawa

Makiko Otani

Makoto Ohwaki

Keigo Tamaki

Ko Osawa

Hidetaka Omine

Hideo Hosoya

Minoru Ichioka

Masaki Yumoto

Yukitoshi Aoyagi

Yusuke Honda

Ryuta Amamoto

Chihaya Adachi

Yoshika Hatasako

To provide a temperature adjustment stage that can efficiently heat a cartridge in accordance with necessity of heating each well. A temperature adjustment stage for heating a cartridge in which a plurality of wells that store a liquid are formed. The cartridge is used in an inspection system that detects an object captured by an immunoreaction, the wells include a labeled antibody well that stores a labeled antibody that labels the object, and there is provided a structure that does not heat the labeled antibody well.

Temperature adjustment stage

A method for detecting an analyte according to the present invention includes: a first step of supplying a specimen to a detection device having a first ligand that is immobilized on a substrate and is capable of specifically binding to the analyte, the specimen being supplied onto the substrate of the detection device, and then causing the analyte included in the specimen to bind to the first ligand; a second step of supplying, onto the substrate, a second ligand that is labeled with a marker and is capable of specifically binding to the analyte, and then causing the second ligand to bind to the analyte bound to the first ligand; and a third step of measuring the second ligand bound to the analyte, wherein in the second step, carboxymethyl dextran is supplied onto the substrate.

Method for detecting analyte

The present invention provides a method for removing liquid from the interior of a flow channel tip, which enables both to reduce the amount of liquid remaining and prevent the time spent removing the liquid from being longer than necessary. The method comprises: suctioning a liquid within a flow channel, the liquid being suctioned into the interior of a liquid suction implement inserted into a first through-hole of a flow channel tip; and removing the liquid within the flow channel. This method comprises: a first suction step for suctioning some of the liquid within the flow channel at a first suction speed; and a second suction step for suctioning the liquid remaining within the flow channel at a second suction speed that is less than the first suction speed, the second suction step being performed in continuation from the first suction step.

Method for removing liquid, and liquid operation device

A surface plasmon resonance fluorescence analysis device has a chip holder for holding an analysis chip, a light source for irradiating excitation light, an angle adjustment unit for adjusting the angle of incidence of the excitation light in relation to the interface of a prism and metal film of the analysis chip, an excitation light reflection filter, a first optical sensor for detecting the fluorescence emitted from the analysis chip and transmitted through the excitation light reflection filter, a second optical sensor for detecting the plasmon scattered light emitted from the analysis chip and reflected by the excitation light reflection filter, and a control unit for controlling the angle adjustment unit. The control unit determines an enhancement angle on the basis of the plasmon scattered light detection results of the second optical sensor.

Surface plasmon resonance fluorescence analysis device and surface plasmon resonance fluorescence analysis method

To provide a gas analysis device comprising: a cell; a light source; and a detector, wherein two or more types of gaseous components contained in the gas are measurement targets, a mid-infrared light with a wavelength that is caused to match the absorption spectrum of the measurement target gaseous components is output from the light source, and concentrations of the gaseous components are obtained based on light intensity detected by the detector. The gas analysis device sets a cumulative measurement time for the mid-infrared lights with the wavelengths for respective ones of the measurement target gaseous components; and controls at least one of an output time of the light source and a detection time of the detector in accordance with the cumulative measurement times, thereby efficiently measuring the plurality of types of gaseous components contained in the gas by using the mid-infrared lights with the plurality of wavelengths.

Gas analysis device and gas analysis method

The detection of rare cells can be achieved with high efficiency, without deteriorating the sensitivity of the detection. A detection method which enables the above-mentioned detection comprises: a first step of carrying out a pretreatment for removing erythrocytes from blood to prepare a cell suspension containing leukocytes and rare cells; a second step of providing all of the cells contained in the cell suspension produced in the first step onto an observation area having multiple holes formed thereon; a third step of taking an optical image of the cells that have been provided on the observation area; and a forth step of detecting the rare cells from the image obtained by the image taking in the third step.

Method for detecting rare cell on observation region

A method for producing bacteria belonging to the genushaving excellent viability even under various conditions with different environmental factors, novel bacteria belonging to the genusobtained by the method, and a method for detecting the bacteria are provided. By subculturing and storing bacteria belonging to the genusalternately in systems under conditions with different environmental factors, the bacteria belonging to the genusexhibiting excellent viability under all the conditions used for the alternate subculturing and storing can be produced.

[object Object]

The present invention provides a solid support for performing steps of isolation of cell or extraction and purification of nucleic acid, safely, easily, efficiently, and with high yield in the genetic test for investigating the presence of pathogenic bacterial infection. A solid support for binding with cell as an embodiment of the above-described solid support, comprises a polypeptide having capability of binding with my colic acid-containing glycolipid which is immobilized on the surface of a carrier. In addition, a solid support for binding with nucleic acid as another embodiment of the above-described solid support, comprises a polypeptide having capability of binding with nucleic acid which is immobilized on the surface of a carrier.

Solid support

Skin preparations for external use and cosmetics which contain a fermented soybean extract prepared by extracting with an organic solvent a fermentation product obtained by treating a soybean extract with one or more microorganisms selected from bifidobacteria. These preparations are excellent in the effects of relieving wrinkles and ameliorating rough skin.

Skin preparations for external use

Hyaluronic acid can be produced efficiently and economically by culturing a strain belonging to a Streptococcus, which has hyaluronic acid producing ability, is hyaluronidase-nonproductive and shows anhemolytic property, and then collecting the hyaluronic acid from the resultant culture. The strain may preferably be Streptococcus zooepidemicus, especially, Streptococcus zooepidemicus YIT 2030 (FERM BP-1305). The hyaluronic acid has a high molecular weight and is useful in providing a cosmetic composition having excellent moisturizing effects and superb feeling of application.

Novel production process of hyaluronic acid and bacterium strain therefor

Growing community of inventors

Tokyo, Japan

Koji Miyazaki