Canon Kabushiki Kaisha

Shionogi Company Limited

Nissan Motor Company Limited

Ricoh Company, Ltd.

Honda Motor Co., Ltd.

Agency of Industrial Science and Technology

Fuji Capsule Co., Ltd.

International Business Machines Corporation

Star Micronics Company Limited

Nihon Kohden Corporation

Koji Masuda

Satoshi Suzuki

Tomoyuki Ogawa

Takao Ogata

Kensaku Kusaka

Kazuhiro Hasegawa

Masanao Inagaki

Eiichi Kojima

Shigeo Kimura

Hisaaki Senba

Yoshinori Hayashi

Seizo Suzuki

Toru Yamada

Hiroyuki Kai

Yuji Sakemi

Yuji Bessho

Fujio Mizukami

Manabu Katou

Naoki Yoshikawa

Hidekazu Maruta

Shiro Kida

Naotake Kobayashi

Takahiro Noguchi

Yoshiyuki Eto

Yuta Inoue

Hiroyuki Tobinaga

Manami Masuda

Shuichi Sugiyama

Shinji Hanada

Mitsuhiro Yonehara

Mado Nakajima

Tsuneji Sano

Naoki Nishimura

Takayuki Ishikawa

Kenji Kato

Tomoyuki Sakamaki

Akihiko Sato

Ryoma Taguchi

Yusuke Ishida

Hiroyuki Suhara

Masao Tokunari

Tadashi Fukuda

Tsuyoshi Watanabe

Fumitake Hirobe

Takayuki Ishihara

Matsuomi Nishimura

Kota Arimoto

Yoshiyuki Shimokawa

Manabu Takano

Takeo Yamamoto

Nobuyuki Tanaka

Akira Kugimiya

Kazuhiko Watanabe

Hsiang Han Hsu

Noriyuki Kurose

Hideki Fujita

Shuhei Kondo

Naoto Shikano

Nobuo Chomei

Satoru Tanaka

Tomoki Murozono

Kazuki Tanaka

Maki Kamikubo

Junichi Mine

Terukazu Kato

Takuya Ikeda

Mitsunori Nishino

Rie Hirayama

Yosuke Kondo

Keiko Igarashi

Yusuke Ichihashi

Motohiro Kawamura

Rikiya Tanabe

Hyuga Masu

Kyohei Hayashi

Tetsuo Ito

Takuji Nakatani

Keiichi Sawamura

Riki Toyooka

Yoshihiko Watanabe

Yuki Obatake

Mikayo Hayashi

Chiemi Hayashi

Satoshi Kasuya

Akihiko Hayano

Hiroshi Nakano

A vehicle door lock device for a door of a vehicle includes: a mechanical changeover mechanism switchable between a mechanical lock mode in which a motion of a door handle lever is not transmitted to a latch and a mechanical unlock mode in which the motion of the door handle lever is transmitted to the latch; an actuator capable of causing the mechanical changeover mechanism to switch from the mechanical unlock mode to the mechanical lock mode; and a controller configured to control the actuator. The controller is configured to, when the controller has determined that any one of a plurality of conditions for re-locking is met and the mechanical changeover mechanism has switched from the mechanical lock mode to the mechanical unlock mode, immediately activate the actuator to cause the mechanical changeover mechanism to switch from the mechanical unlock mode to the mechanical lock mode.

Vehicle door lock device

According to an embodiment, a management system includes a vehicle management device configured to manage parking of a vehicle in a parking space and delivery of the vehicle from the parking space, and a vehicle conveying device configured to be able to convey the vehicle in forward-backward and widthwise directions of the vehicle. The vehicle management device includes a controller configured to control the vehicle conveying device so that the vehicle is conveyed to the parking space when a request for parking the vehicle located within a section where parking in the parking space is able to be requested has been received.

Management system, management device, management method, and storage medium

A soft capsule film composition, comprising: (A) a native gellan gum; (B) one or more hydrophilic polysaccharides; (C) a starch or modified starch; (D) a plasticizer; and (E) water, wherein a gelling agent other than the native gellan gum and the one or more hydrophilic polysaccharides is not an essential component. The soft capsule film composition shortens drying time at room temperature, suppresses the stickiness of the surface of a film sheet, imparts film sheet strength which can withstand continuous production in factory manufacturing with a rotary die filling machine or the like, and enables the manufacture of a good soft capsule with high adhesiveness. For this reason, the soft capsule produced using the soft capsule film composition can be utilized for various uses such as drugs, quasi drugs, cosmetics, and foods.

Soft capsule film composition

An optical connector device is provided. The optical connector device includes a semiconductor package including a receptacle and a lid. The optical connector device also included an adapter attached to the lid of the semiconductor package, and a connector removably attached to the adapter. The adapter includes a convex part adapted to fit into an adapter opening of the lid, an adapter recess adapted to accommodate at least a portion of the connector, and a first retainer in the adapter recess to removably attach the connector to the adapter at a predetermined position. The connector includes an optical fiber array corresponding to the receptacle and extending in a vertical direction with respect to a plane of the semiconductor package, a second retainer used in conjunction with the first retainer, and a biasing member to bias a portion of the connector toward the semiconductor package.

Optical connector device with lid

Novel compounds having D3 receptor antagonistic activity are provided. A compound represented by formula (I): wherein

Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect

Provided are a novel compound having an antagonistic activity for the P2Xreceptor, and a pharmaceutical composition having an antagonistic activity for the P2Xreceptor. A compound represented by Formula (I): wherein Zis C(R) or the like; Ris a hydrogen atom or the like; Zis C(R)(R) or the like; the dashed line represents the presence or absence of a bond; when the dashed line represents the presence of a bond, then Ris absent; Rand Rare each independently a hydrogen atom or the like; Ring Q is a substituted or unsubstituted 5-membered non-aromatic heterocycle or the like; Yis O or the like; Ris a group represented by the formula: &#x2014;(C(R)(R))&#x2014;R; Ris a hydrogen atom or the like; Rand Ris each independently a hydrogen atom or the like; Ris substituted or unsubstituted aromatic carbocyclyl or the like; X is N(R) or the like; Ris a hydrogen atom or the like; Ris substituted or unsubstituted aromatic carbocyclyl or the like; n is an integer from 0 to 4; and m is an integer from 0 to 4, or a pharmaceutically acceptable salt thereof.

Bicyclic nitrogen-containing heterocyclic derivatives and pharmaceutical composition comprising the same

Novel compounds having a D3 receptor antagonistic effect are provided. The compound represented by Formula (IA)': wherein A is S or O; Ris substituted or unsubstituted alkyloxy or the like, Rto Rare each independently hydrogen atoms or the like, ring B is a 4- to 8-membered non-aromatic carbocycle or the like, Ris each independently halogen or the like, r is an integer of 0 to 4, Ris substituted or unsubstituted aromatic heterocyclyl or the like,or a pharmaceutically acceptable salt thereof.

Condensed ring compounds having dopamine D3 receptor antagonistic effect

Novel compounds having a D3 receptor antagonistic activity are provided. The compound represented by Formula (I): wherein Ring A is a non-aromatic heterocycle or the like substituted with substituted or unsubstituted aromatic heterocyclyl or the like; Rto Rare each independently a hydrogen atom or the like; n is an integer of 0 to 3; Ring B is a non-aromatic carbocycle or the like; Ris each independently halogen or the like; r is an integer of 0 to 4; -L- is &#x2014;N(R)&#x2014;C(&#x2550;O), or the like; Ris a hydrogen atom or the like; Ris substituted or unsubstituted aromatic heterocyclyl or the like,or a pharmaceutically acceptable salt thereof.

Cyclic compound having dopamine D3 receptor antagonistic effect

Novel compounds having D3 receptor antagonistic activity are provided. A compound represented by formula (I): whereinring A is a heterocycle, Xis each independently CRR, Xis each independently CRR, Yand Yare each independently a carbon atom or a nitrogen atom,L is &#x2014;N(R)&#x2014;C(&#x2550;O)&#x2014; or the like, W is cyclyl or the like, Rand Rare each independently substituted or unsubstituted alkyl or the like, R, R, Rto R, and Rare each independently hydrogen atoms or the like,p is 1 or 2, q is an integer of 1 to 3, n is an integer of 1 to 4, s is an integer of 0 to 4, or a pharmaceutically acceptable salt thereof.

Provided are a novel compound having an antagonistic activity for the P2Xreceptor, and a pharmaceutical composition having an antagonistic activity for the P2Xreceptor. The compound represented by Formula (I): wherein the symbols are defined in the specification, or a pharmaceutically acceptable salt thereof.

Novel compounds having D3 receptor antagonistic activity are provided. A compound represented by formula (I): 

The invention provides a machine tool capable of facilitating a process of switching product ejecting apparatuses. The machine tool comprises a spindle which rotates a workpiece around an axis of the spindle, an actuator which reciprocates a rod arranged parallel to the axis of the spindle, and a coupler switched between a coupling position and a standby position. The coupler connects the rod and an ejecting shaft inserted in the spindle when held in the coupling position. The coupler is not connected to at least the ejecting shaft when held in the standby position. The ejecting shaft along with the coupler is moved in the direction of the axis of the spindle according to reciprocation of the rod when the coupler is held in the coupling position.

Machine tool

An object is to provide a method of manufacturing a seamless soft capsule that is enteric and excellent in formulation properties. An enteric seamless soft capsule is manufactured by the following steps (a) and (b): (a) preparing an enteric capsule shell liquid comprising gelatin and low methoxy pectin having a degree of esterification of 0 to 40% and a degree of amidation of 0 to 25%, the enteric capsule shell liquid having a viscosity at 50&#xb0; C. of 60 to 127 mPa&#xb7;s; and (b) encapsulating capsule fills with the enteric capsule shell liquid prepared in the step (a) by dripping. Preferably, the jelly strength of the gelatin is 180 to 330 Bloom, an aqueous solution of the low methoxy pectin at a concentration of 2 mass % has a viscosity at 35&#xb0; C. of 8 to 15 mPa&#xb7;s, and the enteric capsule shell liquid comprises 10 to 20 parts by mass of the low methoxy pectin per 100 parts by mass of gelatin.

Method of manufacturing enteric seamless soft capsule

Disclosed is a compound which is useful as an endothelial lipase inhibitor. A pharmaceutical composition having inhibitory activity on endothelial lipase comprising a compound represented by the formula: its pharmaceutically acceptable salt, or a solvate thereof,wherein

Acetic acid amide derivative having inhibitory activity on endothelial lipase

Disclosed is an adamantanamine derivative which is useful as a significant intermediate of an 11&#x3b2;HSD-1 inhibitor. Disclosed is a compound represented by the formula (II): wherein Ris a group represented by the formula: &#x2014;(CRR)m-NR&#x2014;Ror the like.

Adamantanamine derivative

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Tokyo, Japan

Koji Masuda