Sankyo Company, Limited

Canon Kabushiki Kaisha

St-ericsson Sa

Koichi Kojima

Kazuo Koyama

Shigeo Amemiya

Takakazu Hamada

Hiroyoshi Horikoshi

Shinsaku Kobayashi

Hitoshi Kurata

Koki Ishibashi

Kenji Yoshimi

Junichi Sakai

Masao Kozuka

Naozumi Samata

Yuichi Aizawa

Tomowo Kobayashi

Nobuyoshi Iwata

Isao Kaneko

Keiichi Tabata

Kiyoshi Sakai

Torgny Palenius

Takeshi Oshima

Oskar Drugge

Masayuki Iwata

Hiroshi Fukumi

Mitsuo Sugiyama

Junya Ide

Tsugio Kaneko

Masaya Abe

Shiroh Yoshioka

Tatsuya Kori

Atsushi Tomita

Yasuo Wakabayashi

Masaomi Kuraoka

Yukio Hasegawa

Masayuki Ohta

Benny Stenlund

Max Larsson

A receiverand method in the receiver for cell search to find an actual base station having a carrier frequency in a radio communications network. The receiver detects a first signal representative of a base stationby performing slot synchronisation, frame synchronization, cell identification, measurement of a signal quality of the first signal and comparison of the measured signal quality with a first threshold value. When a first signal having a signal quality that is greater than the first threshold value has been detected, the receiver searches for at least one second signal representative of a base station for at least one frequency offset comprised in a set of offsets S. Further, when one or more second signals are detected, the receiver selects the signal with the highest signal quality, and detects a broadcast radio channel representative of a base station for the selected signal.

Receiver and a method therein

An object of the present invention is to provide an apparatus which can manage commodities efficiently by unifying and maintaining commodity codes in order for companies to manage commodities. An apparatus according to the present invention manages product names each consisting of multiple levels and model names below them by means of a product family tree management section and issues commodity codes each consisting of multiple levels for model names by means of a commodity code management section.

Apparatus for issuing commodity codes for commodity model names

Method for treatment of alopecia

A method for treatment or prevention of prostate cancer by administering an effective amount of a compound of the formula (I) or a pharmaceutically acceptable salt or ester thereof. In formula (I) (which follows) , each of R,and R,is a hydrogen atom, a hydroxyl group, a protected hydroxyl group or a lower alkoxy group.

Method for prevention of prostate cancer

An isoxazole compound having the following formula: ##STR1## wherein R.sup.1 represents hydrogen, halogen, alkyl, alkoxy, hydroxyl, alkylthio, amino, alkanoyl, alkanoylamino, alkanoyloxy, alkoxycarbonyl, carboxy, (alkylthio)thiocarbonyl, carbamoyl, nitro or cyano; R.sup.2 represents an amino; m is 2 or 3; n is 1 to 6; ring A represents a phenyl ring, a naphthyl ring or an aromatic heterocycle; and X represents oxygen or sulfur. The isoxazole compound has an excellent monoamine oxidase inhibitory activity, and is useful for treating Parkinson's disease, depression and Alzheimer's disease.

Isoxazole derivatives

A method for treatment or prevention of prostate cancer by administering an effective amount of a compound of the formula (I) or a pharmaceutically acceptable salt or ester thereof. In formula (I) (which follows), each of R.sup.1 and R.sup.2 is a hydrogen atom, a hydroxyl group, a protected hydroxyl group or a lower alkoxy group. ##STR1##

Method for treating prostate cancer

Isoxazole compounds having the following general formula: ##STR1## wherein R.sup.1 represents an optionally substituted aryl group or aromatic heterocyclic group; R.sup.2 represents a hydrogen atom, a halogen atom, an optionally substituted alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a cycloalkenyl group, an alkoxy group, a cyano group, a carboxyl group, an alkanoyl group, an alkoxycarbonyl group or an optionally substituted carbamoyl group; R.sup.3 represents an optionally substituted amino group or a saturated heterocyclic group; X represents an oxygen atom or a sulfur atom; and n is an integer of from 2 to 6. These compounds have excellent monoamine oxidase inhibitory activity and are useful as a therapeutic agent or a preventive agent against nervous diseases such as depression.

Isoxazole compounds useful for the prophylaxis or treatment of nervous

An isoxazole compound having the following formula: wherein R.sup.1 represents hydrogen, halogen, alkyl, alkoxy, hydroxyl, alkylthio, amino, alkanoyl, alkanoylamino, alkanoyloxy, alkoxycarbonyl, carboxy, (alkylthio)thiocarbonyl, carbamoyl, nitro or cyano; R.sup.2 represents an amino; m is 1; n is 1 to 6; ring A represents a phenyl ring or a naphthyl ring; and X represents oxygen or sulfur. The isoxazole compound has an excellent monoamine oxidase inhibitory activity, and is useful for treating Parkinson's disease, depression and Alzheimer's disease.

Compounds of formula (I): ##STR1## �wherein: R.sup.1 is hydrogen, alkyl, aryl-substituted alkyl or aromatic heterocyclic-substituted alkyl; R.sup.2 is: aryl-substituted alkyl, aromatic heterocyclic-substituted alkyl or diarylamino; and R.sup.3 is carboxy or a group of formula --CONHSO.sub.2 R.sup.4 wherein R.sup.4 is alkyl!; and pharmaceutically acceptable salts and esters thereof have valuable 5.alpha.-reductase inhibitory activity and can thus be used for the treatment and prophylaxis of, inter alia, prostatic hypertrophy as well as other disorders arising from excess levels of 5.alpha.-dihydrotestosterone.

Steroid derivatives for the treatment of prostatic hypertrophy, their

Method of making steroid derivatives for the treatment of prostatic

The invented compound ##STR1## is useful for the production of steroidal-17-amides that have 5.alpha.-reductase inhibitory activity.

Steroid derivatives

Compounds of formula (I): ##STR1## [wherein: R.sup.1 is a cyclic amino group, or a dialkylamino group; R.sup.2 a group of formula --NHCHR.sup.3 R.sup.4 wherein R.sup.3 and R.sup.4 are each alkyl aryl or aralkyl, or together form a cycloalkyl group, or R.sup.2 is an aromatic heterocyclic group, or a group of formula --B--S(O).sub.m --R.sup.5 wherein R.sup.5 is a substituted alkyl group, or an aromatic heterocyclic group; B is an alkylene or alkylidene group; m is 0, 1 or 2; A is a group of formula --CH.dbd.CH-- or --(CH.sub.2).sub.n --, where n is 1, 2 or 3]; and salts thereof have valuable anti-ulcer activity.

Anti-ulcer pyridyloxy derivatives, their preparation and uses

The invention includes compounds of formula (I): ##STR1## in which R.sup.1 is hydrogen, alkyl, aryl-substituted alkyl or aromatic heterocyclic-substituted alkyl; R.sup.2 is aryl-substituted alkyl, aromatic heterocyclic-substituted alkyl or diarylamino; and R.sup.3 is carboxy or a group of formula --CONHSO.sub.2 R.sup.4 wherein R.sup.4 is alkyl; and pharmaceutically acceptable salts and esters of the compounds. The compounds have valuable 5.alpha.-reductase inhibitory activity and can thus be used for the treatment and prophylaxis of, inter alia, prostatic hypertrophy as well as other disorders arising from excess levels of 5.alpha.-dihydro-testosterone.

Steroid derivatives for the treatment of prostatic hypertrophy their

Compounds of formula (I): ##STR1## have valuable platelet-aggregation inhibitory activities and may be used for the prophylaxis and treatment of such diseases as thrombosis.

Carbacyclin derivatives, process for their preparation and compositions

Compounds of formula (Ic): ##STR1## having valuable platelet-aggregation inhibitory activities useful for the prophylaxis and treatment of such diseases as thrombosis and pharmaceutical compositions containing said compounds.

Carbacyclin compounds; pharmaceutical compositions and method of use

Growing community of inventors

Tokyo, Japan

Koichi Kojima