Sankyo Company, Limited

Mitsubishi Denki Kabushiki Kaisha

Koichi Hirai

Yuji Iwano

Akira Yoshida

Takahide Nishi

Hiroo Koyama

Kozo Oda

Katsumi Fujimoto

Hiroshi Yasuda

Katsumi Adachi

Akio Torikata

Shuji Takahashi

Mitsuo Nagano

Takeshi Kagasaki

Tetsuo Hiraoka

Yoshiharu Sakaida

Akira Ishii

Hideyuki Shiozawa

Kentaro Kodama

Kaneo Ogawa

Takuzo Nishimura

Tokio Saito

Yukichi Kishida

Kouichi Kitamura

Yoshiki Matsui

Kenkichi Shinkai

In an automotive alternator, a thick-walled guide portion for guiding external air from an opening towards a heat sink main body is formed opposite fins on part of an outer circumferential portion of a bearing housing portion of a rear bracket.

Alternator with cooling air guide formed by bearing housing having guiding portion

A method for preparing compounds of formula (I): ##STR1## wherein: R.sup.1 is hydrogen or a hydroxy-protecting group; R.sup.2 is alkyl, alkoxy, halogen, optionally substituted phenyl or optionally substituted phenoxy; R.sup.3 is optionally substituted pyridyl, optionally substituted quinolyl or phenyl group which has a substituent of formula --CYNR.sup.5 R.sup.6, where Y is oxygen or sulfur, and R.sup.5 and R.sup.6 are each alkyl, aryl or aralkyl, or R.sup.5 and R.sup.6 and the nitrogen to which they are attached together form a heterocyclic group; R.sup.4 is hydrogen or an amino-protecting group; and Z is sulfur or oxygen. The process comprises reacting a compound of formula (II): ##STR2## in which R.sup.8, R.sup.9 and R.sup.10 are the same or different and each represents an alkyl group having from 1 to 4 carbon atoms or a phenyl group, with a compound of formula (III): ##STR3## in which R.sup.11 represents an acyloxy, alkylsulfonyl, arylsulfonyl, alkylsulfinyl or arylsulfinyl group.

Silyl enol ether alkylation process

A process for preparing a compound of formula (I'): ##STR1## comprising reacting a compound of formula (II'): ##STR2## with a compound of formula (III'):

Metal catalyzed displacement process

A compound of the formula ##STR1## in which: R.sup.1' is hydrogen or a carboxy-protecting group;

Carbapenem

Compounds of formula (I): ##STR1## wherein: R.sup.1 is hydrogen or a hydroxy-protecting group; R.sup.2 is alkyl, alkoxy, halogen, optionally substituted phenyl or optionally substituted phenoxy; R.sup.3 is optionally substituted pyridyl, optionally substituted quinolyl or phenyl group which has a substituent of formula --CYNR.sup.5 R.sup.6, where Y is oxygen or sulfur, and R.sup.5 and R.sup.6 are each alkyl, aryl or aralkyl, or R.sup.5 and R.sup.6 and the nitrogen to which they are attached together form a heterocyclic group; is R.sup.4 hydrogen or an amino-protecting group; and Z is sulfur or oxygen; are valuable intermediates in the preparation of carbapenem compounds and retain a desirable configuration during conversion to such carbapenem compounds. Penem and carbapenem compounds having a group of formula --SA' are prepared from a corresponding compound having a substituted thio, sulfinyl or sulfonyl group at this position by reaction with a compound A'SH (where A' is an organic group) in the presence of a salt of a metal of Group II or III of the Periodic Table.

Azetidinone compounds useful in the preparation of carbapenem

Two thiomarinol derivatives, which have antibacterial and anti-mycoplasmal properties, are obtainable from microorganisms of the genus Alteromonas and are named 'thiomarinol B' and 'thiomarinol C'. Thiomarinol B can also be prepared by the oxidation of thiomarinol.

Thiomarinol compounds

N-benzhydryl-substituted heterocyclic derivatives, their preparation and

New compounds useful as immunoregulatory and antineoplastic agents are amino-acid derivatives of formula: ##STR1## wherein: n is an integer from 1 to 5;

Amino-acid derivatives, their preparation and their use as

Novel penicillin and cephalosporin derivatives possessing interferon inducibility and represented by the formula ##STR1## wherein Y represents a hydrogen atom, a halogen atom a nitro group, an alkoxy group or an alkyl group; M represents a protective group for a hydroxyl or carboxyl group; Z represents a group ##STR2## or a group ##STR3## in which D is a hydrogen atom, an acyloxy group, a carbamoyloxy group or a substituted or unsubstituted heterocyclic thio group; A represents a cyano group, a carboalkoxy group or a nitro group; and B represents a hydrogen atom, a cyano group, a carboalkoxy group or a nitro group And process for preparing the same.

Penicillin and cephalosporin derivatives and process for preparing the

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Tokyo, Japan

Koichi Hirai