Sony Corporation

Japan Science and Technology Agency

Kohichi Tanaka

Shinichiro Yamada

Hiroshi Imoto

Hiroyuki Akashi

Momoe Adachi

Hideto Azuma

Kenichi Kitamura

Terue Sasaki

Takayuki Harada

The present invention provides a GLAST knockout mouse lacking the function of an endogenous glutamate transporter GLAST gene, which shows: 1) an intraocular pressure within the normal range; and 2) a reduction in the number of cells in the retinal ganglions when compared with a wild-type normal mouse. Owing to the ocular properties, this knockout mouse is useful as a model for normal tension glaucoma. By using this knockout mouse, a compound useful for the treatment of normal tension glaucoma can be screened.

Mouse with deficiency of glutamate transporter GLAST function

A negative electrode material for a secondary cell for anon-aqueous liquid electrolyte for realizing a high charging/discharging capacity and a high discharging efficiency, a method for producing such material and a non-aqueous liquid electrolyte secondary cell employing such material. The negative electrode material contains at least one carbonaceous material selected from the group consisting of coffee beans, tea leaves, cane sugar, corns, fruits, straws of cereals and husks of cereals, a carbonaceous material derived from a plant-origin high molecular material containing a sum total of 0.2 to 20 wt % of metal elements, phosphorus and sulphur calculated as elements or a carbonaceous material having a diffraction peak between 30.degree. and 32.degree. of the 2.theta. diffraction angle in the X-ray (CuK.alpha.) powder diffraction pattern. For producing the negative electrode material, at least one carbonaceous material selected from the group consisting of coffee beans, tea leaves, cane sugar, corns, fruits, straws of cereals and husks of cereals, or crystalline or fibrous cellulose admixed with at least one of metal elements, phosphorus or sulphur, is sintered for carbonization. The negative electrode material is used for a non-aqueous liquid electrolyte secondary cell having a positive electrode formed of a lithium compound oxide and a negative electrode formed of a carbonaceous negative electrode material capable of doping and dedoping lithium ions as an active negative electrode material.

Negative electrode material for non-aqueous liquid electrolyte secondary

Growing community of inventors

Kanagawa, Japan

Kohichi Tanaka