Chugai Seiyaku Kabushiki Kaisha

Kohichi Endoh

Kazumi Morikawa

Masamitsu Honda

Novel platinum complexes represented by the formula: ##STR1## wherein A is alkylene having carbon atoms of from 1 to 3; R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and are hydrogen or alkyl having carbon atoms of from 1 to 4; X and Y are independently a halogen atom, or combined together to form ##STR2## and l, m and n are independently 0 or 1, and a process for preparing the same are disclosed. These platinum complexes have high antitumor activity and low toxicity, and are easily soluble in water. Therefore, they are very useful as an antitumor agent.

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Tokyo, Japan

Kohichi Endoh