Firmenich Sa

Koenraad P M Vanhessche

Daniel A Dobbs

Valentin Rautenstrauch

Valentin Rautens Trauch

A catalyst of ruthenium (II) comprising bidentate phosphine ligands is described which is obtained by a process that comprises treating equimolar amounts of an appropriate Ru complex and a bidentate diphosphine ligand with an acid of the formula H-Anion, wherein the anion is a non-coordinating anion, said acid being used in a ratio of 1 molar equivalent per mole of Ru complex and the treatment being carried out in a non-coordinating or weakly coordinating medium, under an oxygen-free atmosphere. Said catalyst is useful for the preparation of the preferred isomer of the Hedione&reg;, having the configuration (&plus;)-(1R)-cis, and of many other substrates comprising highly hindered carbon-carbon double bonds.

Growing community of inventors

Basking Ridge, NJ, United States of America

Koenraad P M Vanhessche