Toray Industries, Inc.

Ko Hasebe

Ryoji Hayashi

Seiji Okazaki

Masaki Arai

Satoru Yoshikawa

Sayoko Kanie

Hideki Kozono

Tsukasa Kikuchi

Satoshi Kurosawa

Seiichiro Ozono

Atsushi Otsuka

A method of treatment or prophylaxis of diabetes, obesity, dyslipidemia or metabolic syndrome includes administering an effective amount of a benzylamine derivative represented by Formula (I): wherein, Rrepresents an alkyl group having 1 to 6 carbon atoms; Rrepresents an alkyl group having 1 to 6 carbon atoms; Rand Reach independently represent a halogen atom, an alkyl group having 1 to 6 carbon atoms, a haloalkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and Rrepresents a hydrogen atom or an alkoxy group having 1 to 6 carbon atoms, or a pharmaceutically acceptable acid addition salt thereof.

Therapeutic or prophylactic agent for diabetes, obesity, dyslipidemia or metabolic syndrome comprising benzylamine derivative or pharmaceutically acceptable acid addition salt thereof

The benzylamine derivative represented by the formula below and a pharmaceutically acceptable acid addition salt thereof, and a pharmaceutical containing the derivative or the pharmaceutically acceptable acid addition salt thereof, and a therapeutic or prophylactic agent for pollakiuria or urinary incontinence containing the derivative or the pharmaceutically acceptable acid addition salt thereof are provided. The benzylamine derivative of the present invention and the pharmaceutically acceptable acid addition salt thereof have less possibility of occurrence of side effects than known compounds, and show a better therapeutic effect against pollakiuria or urinary incontinence, so that they can be used as excellent therapeutic or prophylactic agents for pollakiuria or urinary incontinence. 

Benzylamine derivative or pharmaceutically acceptable acid addition salt thereof, and use thereof for medical purposes

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Kanagawa, Japan

Ko Hasebe