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Ludwig Institute for Cancer Research Limited

Knuth Alexander

Lloyd J Old

Yao-tseng Chen

Elke J&auml;ger

Elisabeth Stockert

Matthew J Scanlan

Ali O Gure

Solam Tsang

Michael Pfreundschuh

Jan Wouter Drijfhout

Ugur Sahin

Ozlem Tureci

Ali Gur&eacute;

The invention relates to the isolation of a nucleic acid molecule which encodes a cancer associated antigen. Also a part of the invention is the antigen itself, and the uses of the nucleic acid molecule and the antigen, and peptides derived from it.

Isolated nucleic acid molecule encoding cancer associated antigen, the antigen itself, and uses thereof

The invention relates to antibodies which bind to the cancer associated antigen NY-ESO-1. Both polyclonal and monoclonal antibodies are part of the invention, as are chimeric forms of the antibodies, and binding portions of antibodies. Uses of these antibodies are described. Also described are truncated, recombinant forms of the cancer associated antigen.

Truncated forms of NY-ESO-1 protein

Antibodies which bind to NY-ESO-1 cancer associated proteins, and hybridomas which produce these antibodies

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Frankfurt am Main, Germany

Knuth Alexander