Clondiag Gmbh

Clondiag Chip Technologies Gmbh

Alere Technologies Gmbh

Abbott Rapid Diagnostics Jena Gmbh

Klaus-Peter Möbius

Torsten Schulz

Eugen Ermantraut

Thomas Kaiser

Thomas Ullrich

Jens Tuchscheerer

Thomas Ellinger

Siegfried Poser

Thomas Uhlig

Alexander Von Schenk Zu Schweinsberg

Ralf Ehricht

Gerd Wagner

Joachim Fischer

Karin Adelhelm

A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte.

Methods for detecting an analyte

The invention relates to a reaction vessel, a device and a method for detecting specific interactions between molecular target and probe molecules. The present invention especially relates to a reaction vessel which has a shape and size typical of a laboratory reaction vessel and in which a supporting element with probe molecules immobilized thereon on predetermined regions is arranged on its base surfaces.

Reaction vessel for carrying out array processes

Assays

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Zöllnitz, Germany

Klaus-Peter Möbius