Hamilton Bonaduz Ag

Boehringer Mannheim Gmbh

Klaus Leckebusch

Dirk Schönfuss

Bernd Offenbeck

Armin Panzer

Marco Giardina

Spela Willi

Tino Otte

Meinrad Hofstetter

A spectroscopic sensor assembly for detecting at least one predefined analyte constituent of a measurement fluid, the sensor assembly including a sensor housing; a radiation source; a detector device; a barrier assembly, which is transmissive for measurement radiation and is impermeable to the analyte constituent; a polymer matrix, which absorbs and releases the analyte constituent; a reflector assembly, which has a signal side facing the polymer matrix and facing the barrier assembly; the reflector assembly has a passage extending through the reflector assembly, through which passage the analyte constituent is exchanged between a measurement environment and the polymer matrix, which polymer matrix is located on the signal side of the reflector assembly; the reflector assembly reflects incident measurement radiation back toward the apparatus portion; the sensor assembly having a spacing means different from the polymer matrix that is designed to prevent the reflector assembly from approaching the barrier assembly.

Sensor assembly for spectroscopically detecting substances

A sample dispenser for an analysis device, in particular for an analysis device working according to the principle of liquid chromatography, in particular high pressure liquid chromatography, or gas chromatography, comprising a sample intake for receiving a sample to be analyzed, an inlet through which an eluent can be supplied, an outlet, and an injection valve arrangement, which can be switched at least from an intake position to an injection position, wherein, at least in the intake position and in the injection position, the inlet is in fluid connection with the outlet to deliver the eluent&#x2014;if applicable, having the sample added thereto&#x2014;at least partly to the outlet, wherein, in the intake position, the sample intake is separated from the eluent in a fluid-tight manner, and wherein, in the injection position, the sample in the sample intake can combine with the eluent, wherein the sample dispenser is configured as a disposable component.

Sample dispenser for an analytical device

The invention relates to a syringe, comprising: a syringe body () having an axial inner cavity (), which extends in the direction of a longitudinal axis (LA) of the syringe body () and in which a plunger () can be or is accommodated in such a way that the plunger can be moved in the longitudinal direction, and a needle (), which can be or is connected to the syringe body () at a longitudinal end of the syringe body (), wherein the syringe body () has a coupling segment () at the needle-side longitudinal end of the syringe body (), to which coupling segment () the needle () can be or is fastened by means of a connecting element () that can be slid on in the longitudinal direction. According to the invention, at least one radially inward cavity () is provided on the coupling segment (), which cavity can be brought into engagement or is in engagement with at least one corresponding locking segment () provided on the connecting element ().

Syringe having a mechanical coupling piece

A metering device for use in syringes and pipetting piston-cylinder arrangements; the metering device includes a sealing component and at least one pretensioning component. The sealing component includes a sealing section which has a sealing surface formed on a working surface formed on either the outer surface of the piston rod facing toward the inner wall of the cylinder or on the inner side of the cylinder facing towards the piston rod. The sealing section also has a pretensioning surface for engaging with a plurality of identical pretensioning components for transferring the radial pretensioning force. The plurality of identical pretensioning components are arranged one after the other in the axial direction. The identical pretensioning components include a spring carrier and a plurality of separately formed radial spring segments compliantly supported at least in the radial direction on the spring carrier.

Radial sliding seal subassembly for metering devices, and metering device with such a radial sliding seal subassembly

A metering device for use in syringes and pipetting piston-cylinder arrangements, including a sealing component working together with at least one pretensioning component. The sealing component comprises a sealing segment extending in the axial direction and in the circumferential direction. The sealing segment has a sealing surface facing in a first radial direction for sealing and sliding contact in at least the axial direction, is formed on a working surface formed on the outer surface of the piston rod facing toward the inner wall of the cylinder. The sealing segment also has a pretensioning surface extending in a second radial direction opposite to the first for engaging with the pretensioning component for transferring the radial pretensioning force, where the pretensioning component includes a spring carrier and a plurality of separately formed radial spring segments compliantly supported at least in the radial direction on the spring carrier.

Radial sliding seal with subassembly for metering devices, and metering device with such a radial sliding seal subassembly

A syringe comprises a syringe body () having an axial inner recess () extending in the direction of a longitudinal axis of the syringe body (L), a piston () being guided in an axially moveable manner in said inner recess and contributing to the delimitation of a fluid-receiving volume together with a section of a wall () radially delimiting the inner recess (), and having a needle () that can be or is connected to a longitudinal end () of the syringe body (), wherein the needle () has a coupling geometry () at the longitudinal end () thereof that is closer to the syringe body, wherein the needle () can be connected by said coupling geometry to a counter coupling geometry () of the syringe body (), wherein the geometry composed of the coupling geometry () and counter coupling geometry () comprises an insertion section (), which in the assembled state of the syringe () is received in a coupling recess () of the respectively other geometry, and wherein furthermore safety means () are provided, preventing a retraction movement of the insertion section () from the coupling recess () in the assembled state of the syringe ().

Syringe with exchangeable needle

The invention relates to a radial sliding seal component (), particularly for use in metering devices, such as syringes, pipetting piston-cylinder arrangements, and the like, comprising a sealing component () working together with at least one pretensioning component (), wherein the sealing component () comprises a sealing segment () extending in the axial direction and in the circumferential direction, preferably running in the circumferential direction, on which a sealing surface () facing in a first radial direction for sealing and sliding contact in at least the axial direction is formed on a working surface extending in the axial direction and in the circumferential direction, preferably running in the circumferential direction, and on which a pretensioning surface () extending in a second radial direction opposite to the first is formed for engaging with the pretensioning component () for transferring the radial pretensioning force, wherein the pretensioning component () comprises a spring carrier () and a plurality of separately formed radial spring segments () compliantly supported at least in the radial direction on the spring carrier ().

Radial sliding seal component for metering devices and metering device having such a radial sliding seal component

The unit has three rotors, namely a reagent rotor (1), a sample rotor (2) and a reaction rotor (3). Each rotor has seats for vessels, which are arranged in circles about the respective rotor axis. At least two of the rotors (1, 2) are arranged concentrically to one another. The rotors can be brought into a plurality of rotating positions in which at least one of the openings (5b, 7b, 8b) is located in a predetermined liquid handling position (LH position). A liquid handling unit (LH unit) comprises a liquid transfer needle (18) which is movable by a transfer needle moving apparatus in such a way that the movement path (23) crosses at least one LH position of each circle of openings (5b, 7b, 8b) on each rotor (1, 2, 3). It thus become possible with a simply designed layout to carry out a wide range of heterogeneous immunological analyses in a flexible manner.

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Masein, Switzerland

Klaus Leckebusch