Eli Lilly and Company

Klaus K Schmiegel

Bryan B Molloy

David B Anderson

Edward L Veenhuizen

Walter N Shaw

Ronald R Tuttle

Jack Mills

Lora L Fitch

Samuel James Dominianni

Richard P Pioch

.beta.-Phenethanolamines are effective in promoting growth and improving feed efficiency and leanness in animals.

Growth promotion

Antihyperglycemic compounds selected from the group consisting of C-substituted pentacycloazoles and N-alkyl-substituted pentacycloazoles.

Oral hypoglycemic agents

The present invention provides novel benzamides and sulfonamides, formulations thereof, and intermediates thereto. The benzamides and sulfonamides of the present invention are useful as hypoglycemic agents and, accordingly, a method of using such compounds to lower a mammal's blood glucose level is also provided.

Benzamide and sulfonamide hypoglycemic agents

Optically active N-3-(4-substituted phenyl)propyl-.beta.-phenethanolamines are provided as well as pharmaceutical compositions containing such compounds. A method for effecting weight control in obese animals utilizing optically active phenethanolamine is disclosed. Novel intermediates useful in the preparation of optically active .beta.-phenethanolamines are provided.

Phenethanolamines, compositions containing the same and method for

3-Aryloxy-3-phenylpropylamines and acid addition salts thereof are useful in blocking uptake of monoamines by brain neurons, and are thus effective in treating disorders of sleep, sexual performance, appetite, muscular function, and pituitary function.

Treatment of obesity with aryloxyphenylpropylamines

.beta.-Phenethanolamines are useful as antiobesity agents.

.beta.-phenethanolamine antiobesity agents

Selective biogenic amine uptake inhibitors, 3-substituted phenyloxy-3-phenylpropyldimethylamines.

Substituted phenoxyphenylproply dimethylamines

Optically active N-3-(4-substituted phenyl)propyl-.beta.-phenethanolamines are provided as well as pharmaceutical compositions containing such compounds. A method for effecting weight control in obese animals utilizing optically active phenethanolamines is disclosed. Novel intermediates useful in the preparation of optically active .beta.-phenethanolamines are provided.

Phenethanolamines, compositions containing the same, and method for

3-Aryloxy-3-phenylpropylamines and acid additions salts thereof, useful as psychotropic agents, particularly as anti-depressants.

Arloxyphenylpropylamines

3-Aryloxy-3-phenylpropylamines and acid addition salts thereof, useful as psychotropic agents, particularly as anti-depressants.

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Indianapolis, IN, United States of America

Klaus K Schmiegel