Bayer Aktiengesellschaft

Panalytical B.v.

Buender Glas Gmbh

Bayer Intellectual Property Gmbh

Boehringer Ingelheim Pharma Gmbh & Co Kg

Klaus-Jürgen Steffens

Patrick Garidel

Detlef Beckers

Iris Heep

Vladimir Kogan

Hans-Juergen Hamann

Rolf Daniels

Gert Daube

Hans-Joachim Kern

Klaus List

Marco Schroeder

Jorg Bolze

Christian W Lehmann

Harald G Schweim

Roman Messerschmid

Manfred Wolf

Torsten Schultz-fademrecht

Sandra Zimontkowski

Sabine KÖLLING

Angle dispersive X-ray diffraction is used to test pharmaceutical products including a dosage form inside packaging, for example a tablet inside a blister pack, without removing the dosage form from the packaging. The dosage form is aligned with a measurement system having an X-ray source for generating X-rays, X-ray optics, and an X-ray detector for detection of X-rays. Then, at least one X-ray signature is measured on a predetermined location on the dosage form. The measured X-ray signature is compared with reference X-ray signatures in a data library.

X-ray detection in packaging

Rapidly disintegrating preparations containing at least one active pharmaceutical ingredient and at least one excipient can be obtained by a simple process in which at least the predominant part of the complete composition of the ingredients for the preparation to be produced is granulated, the resulting granules and, where appropriate, the remainder of the ingredients are shaped in the presence of liquid virtually without pressure, and the resulting shaped articles are dried.

Process for the production of rapidly disintegrating, solid pharmaceutical preparations

A method for generating an aerosol includes the step of guiding a gas which flows at supersonic velocity and which has input particles suspended therein in such a way that a compression shock occurs. The input particles are broken down into smaller output particles upon crossing the compression shock. A device for generating an aerosol is also provided.

Method and device for generating an aerosol

Growing community of inventors

Rheinbach, Germany

Klaus-Jürgen Steffens