Merck Patent Gesellschaft MIT Beschrankter Haftung

Klaus Irmscher

Jurgen Uhl

Rochus Jonas

Helmut Prucher

Josef Kramer

Rolf-Dieter Hesch

Klaus-Otto Minck

Hans-Eckart Radunz

Helmut Muller-Calgan

Bernhard Riefling

Hans-Peter Wolf

Ernst Schorscher

Ernst Schulze

Otto Saiko

Halogenohydroxyflavones ##STR1## in which R is alkyl having 1-3 C atoms,

Halogenohydroxyflavones

Flavanone intermediates for halogenohydroxyflavones

Sulfur-containing 6-ketoprostaglandins of the formula I ##STR1## in which D is a bond, alkylene having 1-3 C atoms, cis-alkenylene having 2-5 C atoms or alkinylene having 2-5 C atoms,

Sulfur-containing 6-ketoprostaglandins

Imidazo(4,5-c)pyridines of the formula ##STR1## wherein X is O, S or NH;

Gaba-agonistic imidazo(4,5-c)pyridines useful as pharmaceuticals

Adenosine derivatives of formula I ##STR1## wherein X is F, Cl or Br and n is 1 or 2, and their physiologically acceptable acid addition salts, are valuable psychopharmacological agents.

Use of adenosine derivatives as psychopharmacological agents

Adenosine derivatives of formula I ##STR1## wherein R is H, F, Cl, Br or CF.sub.3, and their physiologically acceptable acid addition salts, are valuable anticonvulsants.

Use of adenosine derivatives as anticonvulsants

Tetralone and indanone compounds of the formula ##STR1## wherein R.sup.1 is H, OH, alkoxy of 1-4 carbon atoms, cycloalkoxy of 3-6 carbon atoms, F, Cl, Br, NO.sub.2, monoalkylamino or dialkylamino, wherein each alkyl is of 1-4 carbon atoms, alkanoyloxy of 1-6 carbon atoms or alkanoylamino of 1-4 carbon atoms; R.sup.2 is OH or alkoxy of 1-4 carbon atoms or R.sup.1 and R.sup.2 collectively are methylenedioxy; R.sup.3 is H or CH.sub.3 ; Ar is phenyl or phenyl substituted by up to 5 of alkyl of 1-4 carbon atoms, alkoxy of 1-4 carbon atoms, F, Cl, Br or CF.sub.3 ; n is 1 or 2, and physiologically acceptable acid addition salts thereof, are central nervous system depressants.

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Darmstadt, Germany

Klaus Irmscher