General Electric Company

Global Life Sciences Solutions Germany Gmbh

Whatman Gmbh

Klaus Hochleitner

Wei Zhang

Suzana Kiel

Yanju Wang

Rong Hou

Bing Zhang

Alexander Schenk

Marcel Thieme

Wei Sun

Georg Peter Danisch

Bing Shang

Wolfgang Thamm

Daniela Katarzynski

In a lateral flow test (LFT) device, the liquid conduit elementis formed from a substrateorhaving at least two layers, including a first layerornot exceeding 75 &#x3bc;m in thickness formed from a porous material for wicking liquid, and a second layerorof additional thickness formed from a generally non-porous polymer material acting as backing layer. The layered arrangement is incorporated into an LFT device to reduce sample volume requirements.

Lateral flow testing

Disclosed is a method and apparatus for manufacturing a continuous web of polymeric membrane and for continuous downstream processing of said web. The apparatus () comprises: a casting station () for casting the continuous web (M); a carrier () for carrying the web downstream; a membrane drier () downstream of the carrier, for drying the web; and a brushing station () downstream of the drier for brushing the web. Said drier is located immediately downstream of the carrier, and upstream of said brushing station. The apparatus () further includes an additional drying station () downstream of the brushing station (). Brushing after drying retains more surfactant in the membrane which is useful for certain applications. In addition, initial drying eliminates virtually all solvents from the membrane, but leaves some non-solvent (e.g. water) within it, which in turn fixes the surfactant on the nitrocellulose fibers, which improves significantly the consistency and reproducibility of the membrane.

Polymeric membranes

A method comprises: sorbing a sample solution comprising nucleic acids to a sample receiving portion of a quartz fiber filter by contacting the sample solution with the sample receiving portion; and washing the sample receiving portion while keeping most of nucleic acids around the sample receiving portion by flowing a wash solution through the sample receiving portion under a wicking force directed away from the sample receiving portion. An associated apparatus is also provided.

Method and apparatus for isolating nucleic acids

A membrane filteris disclosed comprising cellulous materialallowing the transition of fluid therethrough, and, in a substantially dry state, said membrane comprising also a salt of deoxycholic acid. Optionally, the air side of the membrane (the side facing away from the screen or belt used to manufacture the membrane) faces the sample fluid during use of the membrane. A method of manufacture of the membrane material is disclosed also, employing deoxycholic acid as a surfactant, to improve the recovery rate of the membrane filter in use.

Membrane filter including bile acid and a method of manufacturing the same

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Dassel, Germany

Klaus Hochleitner