Bayer Aktiengesellschaft

55pharma Drug Discovery & Development Ag

Klaus Frobel

Erwin Bischoff

Hartwig Muller

Martin Scheer

Friedrich Berschauer

Anno De Jong

Olga Salcher

Johannes-Peter Stasch

Andreas Knorr

Peter Fey

Hans-Georg Dellweg

Jan-Bernd Lenfers

Martin Beuck

Michael Matzke

Dieter Habich

Arnold Paessens

Rainer Neumann

Rudi Grutzmann

Christian Kohlsdorfer

Jutta Hansen

Burkhard Fugmann

Gert Streissle

Bruno Rosen

Jurgen Reefschlager

Karlheinz Weber

Guenther Karmann

Karl-Heinz Weber

Thomas Henkel

Leonhardt Bauer

Immanuel Adorjan

Clemens Fürnsinn

The invention relates to new pseudopeptides having an antiviral action, oft he general formula (I) ##STR1## with the meanings given in the description for the substituents, to a process for their preparation and to their use as antiviral agents, in particular against cytomegaloviruses.

Pseudopeptides having an antiviral action

The invention relates to substituted dibenz-oxa-thiocinone-12-oxides and -12,12-dioxides of the general formula I ##STR1## in which R.sup.1 to R.sup.6 and Y have the meaning indicated in the description, to processes for their preparation and to their use in medicaments, in particular in circulation-influencing medicaments.

Substituted dibenz-oxa-thiocinones, -12-oxides and -12,12-dioxides, a

A method of treating a patient to reduce or prevent an acute or chronic inflammation or an ischaemic state which comprises administering to such patient an effective amount therefor of efomycin A, E or G.

Efomycins A, E and G as antiinflammatory agents

Cardioactive compounds of the formula ##STR1## in which R.sup.1 and R.sup.8 and R.sup.14 and R.sup.15 can be hydrogen or various organic radicals.

Circulation-active dibenzo[1,5]dioxocin-5-ones

The present invention relates to the use of microbiologically prepared compounds and their mixtures, which are called efomycins, as performance promoters in farm animals and processes for their preparation, and furthermore new efomycins and their mixtures as new chemical compounds. The invention also relates to microorganisms which can be used for the preparation of the efomycins and their mixtures.

Efomycins as performance promoters in animals

An animal growth promoter, efomycin G, is obtained by culturing Streptomycetes strain BS 1261. Efomycin G has the following properties:

Efomycin G and it's use as yield promoter in animals

Promoting the growth of animals with a novel compound, named annomycin, by cultivation of Streptomyces strain BS 572, DSM 3817.

Microbiological production of livestock growth-promoting agent

A novel antibiotic for combating bacteria and promoting animal growth is obtained by cultivating Streptomyces strain BA 9.

Antibiotic for animal feeds

Growing community of inventors

Wuppertal, Germany

Klaus Frobel