Bayer Aktiengesellschaft

Klaus Bauer

Martin Scheer

Theo Schroder

Wilfried Kaufmann

Delf Schmidt

Werner Frommer

Dietmar Schafer

Karl G Metzger

Wolfgang Gau

Jorg Pfitzner

Georg Metzger

The invention relates to the provision of an antimicrobial antibiotic obtained by culturing Actinoplanes strain ATCC 31440 under aerobic conditions in the presence of sources of carbon and nitrogen and in the presence of trace amounts of minerals. In addition to their use as antimicrobials, the antibiotics of the invention can be used for improving the growth and feed utilization in animals.

Antibiotic, its production and its medicinal use

Strains of Actinoplanes produce an antibiotic substance upon aerobic cultivation. The antibiotic is soluble in water with a pronounced band in the UV absorption spectrum at 267 nm. Methods for preparing and using the antibiotic, both therapeutically and for promoting livestock growth, and composition adapted for these uses are described.

Antibiotic

Strains of Actinoplanes produce an antibiotic substance upon aerobic cultivation. The antibiotic is sparingly soluble in water with a pronounced band in the UV absorption spectrum at 307 nm. Methods for preparing and using the antibiotic, both therapeutically and for promoting livestock growth, and composition adapted for these uses are described.

Growing community of inventors

Wuppertal, Germany

Klaus Bauer