Roche Diagnostics Operations, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-La Roche Ag

Klaus Andreas Bauer-Espindola

Michael Marquant

Christine Nortmeyer

Carina Horn

Reiner Stein

Dieter Heindl

Volker Unkrig

Stefan Quint

Peter Gebauer

Michael Lambertson

Samuel Evgin

Stacy H Duvall

Stacy Hunt Du Vall

Described is an electrochemiluminescence method of detecting an analyte in a liquid sample using a measuring cell having a working electrode for detecting the analyte using an electrochemiluminescence measurement cycle, involving

Reliability indicating method for an electrochemiluminescence method for detecting an analyte in a liquid sample

A test element for electrochemically detecting at least one analyte in a bodily fluid is disclosed. The test element comprises at least one first electrode and at least one second electrode. The first electrode is designed as a working electrode and the second electrode is designed as a counter electrode. The test element comprises at least one capillary capable of receiving a sample of the body fluid. The first electrode and the second electrode are arranged on opposing sides of the capillary. The first electrode and the second electrode are arranged such that during a capillary filling the first electrode and the second electrode are wetted simultaneously and at an equal rate.

Test element for electrochemically detecting at least one analyte

A method for determining an information on an equivalent series resistance is disclosed and comprises: generating at least one excitation voltage signal and applying the excitation voltage to at least two measurement electrodes; measuring a response signal; determining a signal flank from the response signal and determining an ohmic signal portion from one or both of shape and height of the signal flank; and determining the information on the equivalent series resistance from the ohmic signal portion.

Method and device for determining an information on an equivalent series resistance

Test element for electrochemically detecting at least one an analyte

A method for detecting at least one analyte in a body fluid is disclosed comprising performing an optical measurement, wherein at least one test chemical is contacts the body fluid. The test chemical is an optical test chemical adapted to perform at least one detection reaction, wherein at least one optically detectable property is changed due to the detection reaction to provide at least one optical measurement value. At least one impedance measurement is generated wherein at least one alternating electrical signal is applied to the body fluid via the impedance measurement electrodes and at least one answer signal is recorded, and at least one impedance measurement value is generated. At least one evaluation step is performed wherein at least one evaluation algorithm is used, and the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid.

Methods for detecting an analyte and performing a failsafe step in a body fluid using optical and impedance measurements

The present invention relates to a chemical compound or a salt or solvate thereof being an 1-amino-phenazine derivative and to uses thereof. The present invention further relates to a chemistry matrix and to a test element comprising the aforesaid chemical compound. Moreover, the present invention relates to a method for determining the amount of an analyte in a sample, comprising contacting said sample with a chemistry matrix according to the present invention, estimating the amount of electrons liberated or consumed by the chemistry matrix in the presence of said liquid sample, and thereby determining the amount of an analyte in a liquid sample.

Phenazinium mediators

Growing community of inventors

Mannheim, Germany

Klaus Andreas Bauer-Espindola