Egis Gyogyszergyar

Egis Gyogyszergyar Rt.

Other

Egis Pharmaceutical

Klara Reiter Nee Esses

Zoltan Budai

Tibor Mezei

Lujza E Petocz

Gabor Gigler

Marton Fekete

Gyula Simig

Istvan Gacsalyi

Gabor Blasko

Eniko Szirt Nee Kiszelly

Katalin Szemeredi

Maria Szecsey Nee Hegedus

Istvan Gyertyan

Karoly Magyar

Jozsef Reiter

Andras Egyed

Gizella Zsila

Attila Nagy

Laszlo Puskas

Eva Furdyga

Laszlo Kapolnai

Lajos Fekete

Valeria Hoffmann

Attila Mandi

Jozsef Barkoczy

Frigyes Gorgenyi

Kalman Nagy

Aranka Lay Nee Konya

Imre Klebovich

Margit Csorgo

Judit Bajnogel

Endre Rivo

Klara Kazo Nee Daroczi

Ilona Sztruhar

Eniko Szirt Nee Kislelly

Aniko Kovacs

Erika Karaffa

Eniko Sziri Nee Kiszelly

Gyongyi Vereczkey Nee Donath

Judit Szego

Laszlo Koncz

Eniko Sziri neKiszelly

Istvan Gertyan

The invention refers to a pharmaceutical composition, a process for the preparation thereof and a novel medical use of bicycloheptane derivatives. The pharmaceutical compositions of the invention comprise a bicycloheptane derivative of the formula I ##STR1## wherein said derivative is as defined in the specification herein. The pharmaceutical compositions of the invention are suitable for the treatment of diseases and disorders that are connected with the influence on the cholecystokinin system, especially for preventing the spastic contraction of the gallbladder.

Pharmaceutical compositions containing bicycloheptane ether amines and a

The invention refers to pharmaceutical compositions for the prevention and/or treatment of gastrointestinal diseases connected with infections caused by Helicobacter pylori and a method for the treatment of such diseases. The pharmaceutical composition of the invention comprises as active ingredient a cyclic ketone derivative of the formula I ##STR1## wherein and R.sup.1 mean independently hydrogen or halo;

Pharmaceutical compositions for the prevention and/or treatment a

The invention relates to novel, pharmaceutically active trisubstituted cycloalkane derivatives, a process for the preparation thereof and pharmaceutical compositions comprising the same. The invention also encompasses the use of the said cycloalkane derivatives for the treatment of diseases and for the preparation of pharmaceutical compositions suitable for the treatment of diseases. The compounds according to the invention are characterized by the general formula (I), ##STR1## wherein R represents hydrogen, C.sub.1-4 alkyl or hydroxyl,

Trisubstituted cycloalkane derivatives and process for the preparation

Process for the preparation of 8 -[4 -[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7,9-d ione (buspiron) of the Formula I ##STR1## and the hydrochlorides thereof having high purity by continuously adding a solution of 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-but-2 -inyl]-8-aza-spiro[4.5]decane-7,9-dione of the formula II ##STR2## formed with an inert organic solvent having a concentration of at least 40% by weight to a suspension of a hydrogenation catalyst in an inert organic solvent and optionally converting the 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7 ,9-dione thus obtained into the hydrochloride thereof.

Process for the preparation of high purity buspiron and the

The invention relates to new thioacid amide derivatives, a process for the preparation thereof, compositions, particularly feed additives, premixes and ready-for-use fodders, comprising the same, further to a method for increasing weight gain and improving fodder utilization of domestic animals. The new thioacid amide derivatives of the general formula (I), wherein

Thioacid amide derivatives and fodder compositions containing the same

The invention relates to novel racemic or optically active aminopropanol derivatives of formula I ##STR1## wherein R and R.sup.1 are independently hydrogen atom, halogen atom, lower alkoxy, or together represent a methylene dioxy group,

Aminopropanol derivatives, process for their preparation and

This invention relates to fodder compositions, particularly feed additives, premixes and ready-for-use fodders, and a method for increasing weight-gain and improving fodder utilization of dimestic animals. The compositions according to the invention comprise as active ingredient a compound of the general formula (I), ##STR1## wherein R.sup.1 represents methoxy or hydrogen and

Fodder compositions

This invention relates to novel triazolo derivatives, a process for the preparation thereof, pharmaceutical compositions comprising the same, to the use of the said triazolo derivatives for the treatment of diseases and also for the preparation of pharmaceutical compositions suitable for the treatment of the said diseases. The new triazolo derivatives of the general formulae (Ia) and (Ib), ##STR1## wherein Q represents hydrogen or a heterocyclic group optionally bearing one or more C.sub.1-4 alkyl substituent(s); or a group of the formula SR.sup.1, wherein

Triazolo derivatives and process for their preparation

This invention relates to novel triazolopyrimidine derivatives of formulae (Ia) and (Ib), ##STR1## wherein Q represents hydrogen, a heterocyclic group optionally substituted by a C.sub.1-4 alkyl group and containing one or more oxygen and/or nitrogen atoms or a group of formula

Novel triazolo-pyrimidine derivatives

The new compounds of the general Formula I ##STR1## (wherein A stands for a C.sub.2-4 straight or branched chain alkylene group;

Substituted styrene derivatives

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Budapest, Hungary

Klara Reiter Nee Esses