Pharmacia & Upjohn Ab

Pharmacia Ab

Kjell Berglund

Stefan Lundmark

Otto Skolling

Bo B Gustafsson

Cathrine Brooling

Jimmie Ward

Anna Ahlqvist

A flexible transparent container for improved storage of oxygen sensitive parenterally administerable agents comprising an inner, primary container enclosed in a substantially oxygen impermeable outer envelope with an oxygen absorber, capable of consuming essentially all residual oxygen after the outer envelope is sealed, and for sufficient period also the oxygen penetrating said envelope. The inner container is made of a polypropylene containing flexible polymeric material compatible with lipophilic agents capable of forming both permanent and peelable seals, while the envelope is made of a substantially water impermeable flexible multilayered polymeric material comprising a first outer substantially water impermeable polymeric film with oxygen barrier forming capacity, assembled with a second, inner polymeric film with a supplementary oxygen barrier forming capacity. The container essentially maintains its characteristics after being subjected to sterilization by steam or radiation.

Containers for parenteral fluids

Process for sterilization by radiation and by the use of an oxygen

Growing community of inventors

Jarfalla, Sweden

Kjell Berglund