Hitachi-high-technologies Corporation

Hitachi, Ltd.

The University of Tokyo

Hitachi High-tech Corporation

Kyowa Kirin Co., Ltd.

Hitachi-science Systems, Ltd.

Kiyotoshi Mori

Mitsuru Oonuma

Kosuke Matoba

Masaru Tomioka

Akira Owada

Takayuki Ono

Masao Kamahori

Yusuke Goto

Hideyuki Akiyama

Hiroshi Sasaki

Masahito Ito

Yoko Sato

Hiroyuki Noda

Hironori Kaji

Kazuki Okada

Masato Fukuda

Yoshiaki Yamada

Satoshi Uematsu

Naoki Takemura

Atsushi Ninomiya

Ryoji Inaba

Motohiro Yamazaki

Kisaburo Deguchi

Yoshihiro Nagaoka

Hiroshi Moriya

Takashi Gomi

Kazunori Yanagisawa

Shintaro Kubo

Yoshimasa Yokoyama

Kimihiko Ishii

Ayano Otsubo

Takaaki Hara

Takefumi Yokokura

Masanori Takaki

Kenichiro Takahashi

Kosaku Toyosaki

Norimasa Minamoto

Toshinobu Shirato

Hiroyuki Tanai

Shoji Tomita

Katsunobu Hama

A therapeutic or prophylactic agent for radiation damage associated with radiation exposure, comprising an eosinophil-removing agent as an active ingredient and the like are provided as a technique for efficiently treating or preventing radiation damage associated with radiation exposure. According to the therapeutic or prophylactic agent comprising an eosinophil-removing agent according to the present invention, by suppressing migration and/or infiltration into target tissue and/or proliferation in the tissue of eosinophils and/or inhibiting the activity or function of the eosinophils, pathological conditions such as inflammatory responses and fibrosis of tissue can be suppressed to effectively treat or prevent radiation damage. Moreover, effective radiation therapy can be performed by suppressing radiation damage.

Treatment or prevention method of radiation damage by administration of IL-5 receptor alpha chain binding antibody

A composite structure with high pressure resistance that is suitable for a flow channel is produced by reducing the number of components while maintaining the excellent chemical resistance and high stress tolerance inherent to a glass substrate and a resin substrate. A glass substrate surface is modified with a hydrolyzable silicon compound, and the glass substrate is brought into contact with the resin substrate. Subsequently, the contact surface between the glass substrate and the resin substrate is heated to a temperature from the glass transition temperature to the pyrolysis temperature of the resin substrate, eliminating gaps between the glass substrate and the resin substrate to bring them into close contact with each other, and causing chemical binding or anchor effects between the glass substrate and the resin substrate via the hydrolyzable silicon compound. Thus, the glass substrate and the resin substrate are firmly fixed to each other.

Glass/resin composite structure and method for manufacturing same

Provided are: a flow path switching valve that reduces the pressure load in a contact surface outer peripheral section of the flow path switching valve and inhibits friction between constituent components; and a liquid chromatographic device using the flow path switching valve. The flow path switching valve is provided with a stator having a plurality of through holes and a seal having conduction grooves for causing the through holes to conduct. The seal has a first portion present vertically beneath a region comprising at least a surface of contact with the stator, and a second portion having lower rigidity than the first portion, on the outside of the first portion. Due to this configuration, it is possible to reduce the pressure load when a flow path of a liquid is switched under high-pressure conditions, and inhibit the phenomenon of friction itself.

Fluid switching valve and liquid chromatograph apparatus using the same

A detector for liquid chromatography has light sources that generate light in an ultraviolet region and in a near-infrared region; a flow cell, through which sample liquid flows; an optical system to let light generated from the light sources become incident on the flow cell concurrently; a detection element that detects light in the ultraviolet region that passes through the flow cell; a detection element that detects light in the near-infrared region that passes through the flow cell; and an arithmetic operation part that performs arithmetic operation of a first signal value obtained from the detection element and of a second signal value obtained from the detection element. The arithmetic operation part combines the first signal value and the second signal value to calculate a signal value with a reduced baseline fluctuation resulting from a mobile phase during a gradient analysis.

Detector for liquid chromatography

In a liquid chromatograph, the disulfide adsorption of iron atoms in a filter for a column is avoided and thus peak tailing in a chromatogram is prevented to thereby prevent a lowering in the sample recovery rate. A liquid chromatograph column comprising a hollow tubular column body, a bead-shaped packing material which is packed in the hollow part of the column body, a filter provided with a mesh which has a mesh size smaller than the particle diameter of the packing material, and a cap which presses the filter against the packing material to thereby enclose the packing material within the column body, characterized in that the main component of the filter is nickel or hastelloy.

Liquid chromatograph, liquid chromatograph column and filter for liquid chromatograph column

Liquid chromatograph analyzer

Auto sampler for liquid chromatograph analyzer

Column oven for liquid chromatograph analyzer

Pump for liquid chromatograph analyzer

A pump device which accurately detects a flow rate of a pump, performs real-time control of the flow rate, and thus can suppress a flow rate error caused by occurrence of pulsation. Control of a pump rotation speed by a pressure sensor has low responsiveness in a low pressure region, and a correlation between a pressure and a flow rate is incomplete in a high flow rate region. With this taken into consideration, a flow rate sensor is disposed at an outlet port of a second pump. A position detection sensor detects a point where a first pump is shifted from a suction mode to a discharge mode. Moreover, the flow rate sensor detects that there is no discharge from the pump, and that there is discharge from the pump alone. Accordingly, a controller sets a rotation speed of a motor to a speed double the previous speed (double the normal rotation speed). When the flow rate sensor detects an increase in the flow rate at the outlet port of the second pump, the controller returns the rotation speed of the motor to a normal rotation speed. The rotation speed of the motor is controlled by accurate flow rate detection by the flow rate sensor. Thus, occurrence of pulsation can be suppressed.

Two-unit pump for liquid chromatograph with flow sensor arrangement

Growing community of inventors

Tokyo, Japan

Kiyotoshi Mori