Hitachi, Ltd.

Kiyoshi Tsukada

Toshiaki Kita

Tomonari Morioka

Yasushi Shimizu

Shuhei Yamamoto

Ryoji Inaba

Tomohiro Shoji

Masaya Kojima

Masao Fukunaga

Daizo Tokinaga

Yoshiyuki Okishima

Takayasu Furukawa

Akihiro Suzuki

Seiichi Ugai

Syozo Kasai

A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.

Capillary array

A capillary array includes multiple capillaries and two holding substrates for arranging the aforementioned multiple capillaries in a substantially plane surface by sandwiching at least some of these capillaries mutually. One of the holding substrates has a detection window for transmitting the detected light emitted by a test sample by irradiation of light. Especially, this detection window includes multiple light transmission areas provided to correspond to each capillary to transmit the detected light, and light cut-off areas provided between these light transmission areas to cut off the detected light. These light cut-off areas cut off light reflected from the surface of capillaries and hence improve the SN ratio, thereby ensuring high-precision detection.

Capillary array unit and electrophoresis based thereon

A capillary array comprising multiple capillaries and two holding substrates for arranging the aforementioned multiple capillaries in a substantially plane surface by sandwiching at least some of these capillaries mutually. One of the holding substrates has a detection window for transmitting the detected light emitted by a test sample by irradiation of light. Especially, this detection window comprises multiple light transmission areas provided to correspond to each capillary to transmit the detected light, and light cut-off areas provided between these light transmission areas to cut off the detected light. These light cut-off areas cut off light reflected from the surface of capillaries and hence improve the SN ratio, thereby ensuring high-precision detection.

Capillary array and electrophoresis apparatus

The structure of a capillary head section is made such that the liquid contacting surfaces of a capillary holder, a capillary, and an adhesive form a plane surface, and this shared liquid contacting surface is made a mirror surface with a surface roughness of 3.2 s or less. In the shared liquid contacting surface, the ratio of the total area of the capillaries to the internal diameter area of the capillary holder is made 60 to 73%.

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Mito, Japan

Kiyoshi Tsukada