National Institute of Advanced Industrial Science and Technology

Kiyomitsu Nara

Hisashi Narimatsu

Yuzuru Ikehara

Atsushi Kuno

Yasuhiro Hashimoto

Hiromi Ito

Keiro Shirotani

Yoshinobu Kariya

Kyoka Hoshi

It is intended to develop and provide a method for detecting a particular glycan-isoform rapidly and specifically by a small number of steps. The present invention provides a glycan-isoform detection method comprising quantifying an immune complex formed by the mixing of a test sample with a sugar chain non-reducing terminal residue-binding lectin and an antibody specifically binding to the protein moiety of the glycan-isoform, etc., comparing the obtained amount of the immune complex with the amount of a control immune complex obtained when a control sample is not mixed with the sugar chain non-reducing terminal residue-binding lectin or is mixed with a control protein, and determining the presence or absence of the glycan-isoform of interest in the test sample on the basis of the difference between these amounts.

Glycoform detection method and glycoform detection device

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Fukushima, Japan

Kiyomitsu Nara