Shinwa Chemical Industries Ltd.

Other

Shiseido Company, Limited

Toyohashi University of Technology

Nippon Medical School Foundation

Kiyokatsu Jinno

Hiroo Wada

Yoshihiro Saito

Tsutomu Takeichi

Yutaka Ohtsu

Kenzo Kotera

Makiko Hayashida

Kenji Itoh

Hideo Nagashima

Youkichi Ohno

Hisashi Matsuura

The invention provides a method for simple, rapid and inexpensive analysis of drugs such as nicotine and other drugs which are accumulated in biological samples of addictive drugger of tobacco, stimulant drug and the like. The method comprises the steps of introducing the biological sample into an injection needle, inserting the needle into an injector of a chromatograph and injecting a carrier into the needle to conduct chromatography treatment.

Simple analysis method of drugs

Described is a copolymer of methacrylic acid and ethylene glycol dimethacrylate which does not have any specificity to general organic solvents, can thus adsorb wide variety of the organic solvents, shows almost no desorption-adsorption hysteresis and therefore, is excellent in desorption characteristics. Also described is a method for the preparation of the copolymer; an adsorbent or a concentrating medium comprising the copolymer; a loop used in an injector for chromatography which is packed with the adsorbent or concentrating medium; a needle for solid-phase microextraction (SPME) which is packed with the adsorbent or concentrating medium; a kit for the preparation of a sample comprising the needle for SPME; a method for concentrating a sample; and a method for analyzing an analyte present in a sample.

Copolymer, and adsorbent or concentrating medium and needle for solid phase microextraction prepared using the copolymer

A separation column for chromatography or a medium for solid phase extraction, which comprises a hollow capillary and a collected body packed in the hollow capillary and serving as a stationary phase, the collected body comprising long fibers having an adsorbing ability selective towards a target solute and arranged in the axial direction of the capillary, and a sample injection system which comprises the foregoing hollow capillary incorporated into a loop of a valve or a passage connecting two valves, the valve(s) being used as an injector for the chromatography. The use of the polymeric long fibers, which have chemical structures specially designed so that they can specifically interact with a target substance (a solute or an analyte) to be analyzed, permits the selective or preferential extraction and/or concentration of the solute.

Separation column from chromatography, medium for solid phase extraction and sample injection system for chromatography

Separation column for chromatography, medium for solid phase extraction and sample injection system for chromatography

Modified silica gel in chromatography packing material

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Toyohashi, Japan

Kiyokatsu Jinno