Industry-Academic Cooperation Foundation Gyeongsang National University

Kiwon Lee

Ki Hun Park

Ji Yun Yoo

Sangseok Oh

Kwang Dong Kim

Soojong Park

Hyung Won Ryu

Dae Wook Kim

A skin whitening composition includes β-mangostin or a cosmetically acceptable salt thereof as an effective ingredient. β-Mangostin represented by Chemical Formula 1 suppresses the expression of tyrosinase and TRP-1 (tyrosinase-related protein-1) and induces autophagy of a melasosome. As such, it was confirmed that the β-mangostin not only suppresses melanin production but also exhibits the effect of removing previously formed melanin. Accordingly, the β-mangostin can be advantageously used as a functional material for skin whitening and skin lightening.

Composition for skin whitening comprising β-mangostin as effective ingredient

A skin whitening composition includes amorphigeni or a salt thereof as an effective ingredient. Amorphigeni suppresses the expression of tyrosinase and induces autophagy on melanosomes. As such, it was confirmed that amorphigeni not only suppresses melanin production but also exhibits the effect of removing melanin previously produced by &#x3b1;-MSH (melanocyte-stimulating hormone). Accordingly, amorphigeni can be advantageously used as a functional material for skin whitening and skin lightening.

Composition for skin whitening comprising amorphigeni as effective ingredient

Growing community of inventors

Gyeongsangnam-do, South Korea

Kiwon Lee