Otsuka Pharmaceutical Company, Limited

Otsuka Pharmaceutical Factory, Inc.

Kinue Ohguro

Hidetsugu Tsubouchi

Tetsuya Sato

Hiroshi Ishikawa

Takashi Okamura

Kinji Hashimoto

Yasuhide Inoue

Kazuyoshi Miyata

Koushi Iwata

Akifumi Hagi

Hitoshi Ohno

Motoya Kikuchi

Hirofumi Sasaki

Makoto Matsumoto

Shin Miyamura

Isao Takemura

Takumi Sumida

Yoshikazu Haraguchi

Motohiro Itotani

Masanori Kawasaki

Takeshi Hasegawa

Hiroyuki Hashizume

Tatsuo Tomishige

Kazuho Tanaka

The present invention provides a disinfectant that contains olanexidine in a concentration sufficient to exhibit an effective bactericidal effect, and that has hardly any side effects such as skin irritation. Specifically, the present invention provides a disinfectant containing an aqueous solution that contains olanexidine and at least an equimolar amount of gluconic acid, and substantially contains neither an acid other than gluconic acid nor a salt of the acid other than gluconic acid.

Aqueous solution of olanexidine, method of preparing the aqueous solution, and disinfectant

The present invention provides a 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound represented by the following general formula: (1) in the above formula (1), R1 represents a hydrogen atom or C1-C6 alkyl group, n represents an integer of 0 to 6, R1 and &#x2014;(CH2)nR2 may form a spiro ring represented by the formula (30) below, together with the adjacent carbon atom (in the formula below, RRR represents a piperidyl group which may have substituents on the piperidine ring), (30) and R2 represents a benzothiazolyloxy group, quinolyloxy group, pyridyloxy group or the like. The present compound has an excellent bactericidal action against, multi-drug-resistant, and atypical acid-fast bacteria. 

2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis

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Tokushima, Japan

Kinue Ohguro