Other

Humantec Ltd.

Kiminari Ito

Teruaki Sekine

Kenzo Bamba

Yasuyuki Kuroiwa

Norio Shimizu

Tomohiro Yamaguchi

Activated lymphocytes derived from cord blood are excellently effective for preventing and treating various types of tumors and various types of infection. With interleukin 2 and/or anti-CD3 antibody, the lymphocytes derived from the cord blood is prepared by segregating lymphocytes from the cord blood and proliferating the segregated lymphocytes directly in vitro or segregating monocytes from cord blood and proliferating the monocytes in vitro. Also, the cord blood-derived activated lymphocytes can be effectively used for preventing recurrence of the diseases and promoting the take of stem cells or other organs.

Cord blood-derived activated lymphocytes, preparations containing said lymphocytes as main ingredient and method and kit for producing said preparations

Compositions or medicaments comprising allogenic activated-CD4&plus; cells as the main ingredient, which are attributable to an organ or bone marrow transplantation donor, have an extremely beneficial effect for preventing recidivation of a tumor and remedying various infections such as viral infections, and autoimmune diseases such as phagocytosis, without causing any serious GVHD. The allogenic activated-CD4&plus; cells can be produced by separating lymphocyte cells or CD4&plus; cells from peripheral blood of the donor or removing CD8&plus; cells from the peripheral blood of the donor by using anti-CD8&plus; antibodies to obtain CD4&plus; cells and proliferating the CD4&plus; cells thus prepared in proliferation activator.

Compositions comprising, as the main ingredient, allogenic activated-C4&plus; cells and method for producing and using the same

Growing community of inventors

Hokkaido, Japan

Kiminari Ito