Ube Industries, Inc.

Kimihiko Yoshimura

Masahiko Hagihara

Shigeyoshi Nishino

Hidetaka Shima

Yukinori Wada

Yasunori Tsuzaki

Yasuhiro Aga

Tetsuro Shimano

Naoto Suzuki

Masao Maruyama

Nobuyoshi Fujii

The present invention relates to a benzazepinone compound represented by the following formula (I): wherein Rrepresents a C-Calkyl group or halogeno C-Calkyl group, Rrepresents a carboxyl group which may be protected, and Y represents a group represented by the formula (II): wherein Z represents CH or a nitrogen atom,or a pharmaceutically acceptable salt thereof.

Benzazepinone compound

An object of the present invention is to provide an industrially suitable process for preparing an imidazolidin-2,4-dione compound which is safe, simple and easy to prepare the imidazolidin-2,4-dione compound with high yield, which is a useful compound, for example, as a material for decomposing a harmful halogenated aromatic hydrocarbon compound such as dioxin, etc., an electroless silver plating solution for electronic parts, or a diazo copying material, etc. This object can be solved by a process for preparing an imidazolidin-2,4-dione compound which comprises subjecting a 4,5-dihydroxy-2-imidazolidinone compound, (1) to dehydration reaction in the presence of an acid catalyst(s); or (2) to reaction at 100 to 300&#xb0; C. Or, it can be solved by a process for preparing an imidazolidin-2,4-dione compound which comprises reacting a mixed solution of a urea compound, glyoxal, and a base at 20 to 300&#xb0; C. Also, an object of the present invention is to provide a method for acquiring a 4,5-dihydroxy-2-imidazolidinone from an aqueous solution containing a 4,5-dihydroxy-2-imidazolidinone by a simple and easy method. This object can be solved by a process for acquiring a solid state 4,5-dihydroxy-2-imidazolidinone compound which comprises mixing an organic solvent with an aqueous solution containing a 4,5-dihydroxy-2-imidazolidinone compound, and subjecting the mixture to azeotropic distillation.

Process for preparing imidazolidin-2,4-dione compound and method for acquiring solid state 4,5-dihydroxy-2-imidazolidinone compound

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Ube, Japan

Kimihiko Yoshimura