Novan, Inc.

Ligand Pharmaceuticals, Inc.

Kimberly McHale

Nathan Stasko

Ryan Doxey

Stanley J Hollenbach

The present invention relates generally to topical antiviral compositions, delivery systems, and methods of using the same.

Topical antiviral compositions, delivery systems, and methods of using the same

Provided herein are compositions useful for treating inflammation in a subject and methods of decreasing inflammation in the skin, mucosa, and/or eye of a subject comprising applying a pharmaceutical composition that includes an NO-releasing compound to the skin, mucosa, and/or eye of the subject in an amount sufficient to decrease inflammation.

Compositions for treating inflammation and methods of treating the same

Provided are combinations comprising terbinafine or a pharmaceutically acceptable salt thereof and a NO source. The combination may be a synergistic combination. Also provided are methods of treating and/or preventing a fungal infection in a subject comprising administering terbinafine or a pharmaceutically acceptable salt thereof to the subject; and administering a NO source to the subject, thereby treating and/or preventing the fungal infection in the subject. The dose of terbinafine or a pharmaceutically acceptable salt thereof and the dose of the NO source administered to the subject may achieve a synergistic effect.

Combinations and methods for the treatment and/or prevention of fungal infections

The present invention relates generally to topical antiviral compositions and methods of using the same.

Growing community of inventors

Hillsborough, NC, United States of America

Kimberly McHale