Modernatx, Inc.

Kimberly Hassett

Luis Brito

Orn Almarsson

Joseph Schariter

Mike Smith

Shinu John

Andrea Carfi

Jack F Kramarczyk

Phil White

The disclosure features novel methods of producing nucleic acid lipid nanoparticle (LNP) compositions employing a modifying agent after formation of a precursor nucleic acid lipid nanoparticle, the produced compositions thereof, and methods involving the nucleic acid lipid nanoparticles useful in the delivery of therapeutics and/or prophylactics, such as a nucleic acid, to mammalian cells or organs to, for example, to regulate polypeptide, protein, or gene expression.

Methods of making lipid nanoparticles

Aspects of the disclosure relate to methods for producing an antigen-specific immune response to human cytomegalovirus (hCMV) in a subject by administering mRNA vaccines.

Human cytomegalovirus vaccine

Growing community of inventors

Cambridge, MA, United States of America

Kimberly Hassett