Bristol-myers Squibb Compnay

Kimberly D Krampitz

Jingfang Qian Cutrone

Stephen W Mamber

Grace A McClure

Lyndon M Foster

Katie A Thompson

Lisa C Rupar

Todd Peterson

Todd C Peterson

Yue-Zhong Shu

Li-Ping Chang

Susan E Lowe

A novel tyrosyl diester antibiotic is obtained from fermentation of a recombinant strain ofdesignatedWD 15684 (ATCC-202143). The new antibiotic, designated tyrissamycin, exhibits antibacterial activity, particularly against gram-positive bacteria.

Tyrissamycin antibiotic

A novel tyrosyl diester antibiotic is obtained from fermentation of a recombinant strain of,designated,WD 15684 (ATCC-202143). The new antibiotic, designated tyrissamycin, exhibits antibacterial activity, particularly against gram-positive bacteria.

The novel antitumor antibiotics designated stephacidin A and stephacidin B are produced by fermentation of,ATCC-74432. The antibiotics inhibit the growth of mammalian tumors, including particularly prostate carcinoma.

Stephacidin antitumor antibiotics

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Southington, CT, United States of America

Kimberly D Krampitz