Duke University

Immunolight, LLC

Kim Lyerly

Zakaryae Fathi

Frederic Avery Bourke, Jr

Harold Walder

Mark Oldham

Justus Adamson

Takuya Osada

Neil Lee Spector

Paul Yoon

Leihua Liu

David Alcorta

Wayne F Beyer

Mark DeWhirst

Mark W Dewhirst

Wayne F Beyer, Jr

Neil L Spector

Wayne F Bayer

Frederic A Bourke

A method for treating a diseased site in a human or animal body is provided which includes injecting in a diseased site one or more phosphors which are capable of emitting ultraviolet or visible light into the body;

X-ray psoralen activated cancer therapy (X-PACT)

A system for treating a diseased site in a human or animal body. The system includes a pharmaceutical carrier including one or more phosphors which are capable of emitting light into the diseased site upon interaction, a photoactivatable drug for intercalating into DNA of cells at the diseased site, one or more devices which infuse the diseased sited with the photoactivatable drug and the pharmaceutical carrier, an x-ray or high energy electron source, and a processor programmed to control a dose of x-rays or electrons to the diseased site for production of light inside the tumor to activate the photoactivatable drug.

A system (and associated method) for treating a human or animal body. The system has a photoactivatable drug for treating a first diseased site, a first pharmaceutically acceptable carrier including one or more phosphorescent or fluorescent agents which are capable of emitting an activation energy into the body which activates the photoactivatable drug, a first device which infuses the first diseased site with a photoactivatable drug and the first pharmaceutically acceptable carrier, a first energy source which irradiates the diseased site with an initiation energy to thereby initiate emission of the activation energy into the body, and a supplemental treatment device which administers one or both of a therapeutic drug or radiation to the body at a second diseased site or the first diseased site, to provide an immune system stimulation in the body.

X-RAY psoralen activated cancer therapy (X-PACT) with associated treatments

Growing community of inventors

Durham, NC, United States of America

Kim Lyerly