The Dow Chemical Company

Merrell Dow Pharmaceuticals

Kim G Bargeron

George J Quarderer, Jr

Danil Tirtowidjojo

Douglas C Greminger

David L Trent

Thad S Hormel

Cheryl A Tirtowidjojo

David J Koranek

Curtis N Swisher

Erik J Stewart

F Mark Laskovics

David K Winegardner

Bruce G Lovelace

A process of preparing alkylene oxides comprises steps of: (1) optionally forming a hypochlorite solution; (2) contacting chlorine with a solution of a hypochlorite below about 60.degree. C., and a pH of less than about 5.5, with sufficient micromixing to achieve a product hypochlorous acid in a yield of at least about 80 percent; (3) separating at least a portion the hypochlorous acid from an aqueous metal chloride solution wherein the solution is sprayed as droplets; (4) distilling the remaining liquid phase; (5) absorbing the hypochlorous acid and dichlorine monoxide in low-chlorides water to produce a low-chlorides aqueous hypochlorous acid solution; (6) contacting the low-chlorides aqueous hypochlorous acid solution with an olefin in a continuous process to form a olefin chlorohydrin; (7) optionally contacting the olefin chlorohydrin with a base to form a alkylene oxide and a salt solution; and (8) optionally separating the alkylene oxide from the salt solution. (9) optionally removing chlorates from the chloride brine by contacting the chlorates with acid to convert the chlorates to chlorine; and (10) optionally recycling the chlorine. The process yields particularly high yields of the alkylene oxide without substantial production of by-products.

Process for preparing alkylene oxides

This invention relates to an improvement in a process for making 2,6-di-tertiarybutyl-4-mercaptophenol and 4,4-isopropylidenedithio-bis-(2,6-di-tertiarybutylphenol) which comprises reduction of bis (3,5-di-tertiarybutyl-4-hydroxyphenyl)polysulfide with hydrogen gas at a temperature range of from about 20.degree. C. to about 90.degree. C. in the presence of a catalytic amount of cobalt-molybdenum catalyst.

Process for preparing 2,6-di-tertiarybutyl-4-mercaptophenol and

The title compounds are prepared by the reaction of a 2-alkyl-2-oxazoline with hydrogen sulfide in a continuous process wherein both reactants are maintained in the liquid phase throughout the reaction by the use of superatmospheric pressure. This continuous process reduces the reaction time substantially compared to prior art process and also reduces the quantity of by-products.

Preparation of N-(2-mercaptoethyl)alkanamides

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Midland, MI, United States of America

Kim G Bargeron