Danmarks Tekniske Universitet

Københavns Universitet

Chr. Hansen Natural Colors A/s

Kim Binderup

Finn Thyge Okkels

Birger Lindberg Møller

Bjørn Madsen

Rasmus John Normand Frandsen

Rubini Maya Kannangara

Uffe Hasbro Mortensen

Ulf Thrane

Mads Bennedsen

Johan Andersen-Ranberg

Majse Nafisi

Paiman Khorsand-Jamal

Dan Stærk

Kenneth Thermann Kongstad

A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I): heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II): converting in vivo the non-reduced octaketide of step (I) into a C-Caromatic compound of interest (e.g. carminic acid).

Use of octaketide synthases to produce kermesic acid and flavokermesic acid

An isolated glycosyltransferase (GT) polypeptide capable of: (I): conjugating glucose to flavokermesic acid (FK); and/or (II): conjugating glucose to kermesic acid (KA) and use of this GT to e.g. make Carminic acid.

Glycosyltransferase glycosylating flavokermesic acid and/or kermesic acid

Glycosyltransferase glycosylating flavokermesic acid and/or or kermesic acid

Growing community of inventors

Charlottenlund, Denmark

Kim Binderup