Customarray, Inc.

Protein Discovery, Inc.

Combimatrix Corporation

Kilian Dill

Nathan S Lewis

Dean G Hafeman

Richard Caprioli

Jeremy L Norris

John J Cooper, Jr

Charles E Witkowski, Ii

Kristian M Roth

James B Harkins

Daniel Kuban

Andrei Ghindilis

There is disclosed a process and an array for assaying for binding of target molecules to capture molecules on micro array devices, wherein the microarray devices contain electrodes. Specifically, there is disclosed a binding (including nucleotide hybridization) process to detect binding on a microarray wherein the microarray contains electronically addressable electrode devices. There is further disclosed an enzymatically catalyzed oxidation/reduction reaction to take place within a 'virtual flask' region of a micro array wherein the reaction is detected by current changes detected on the addressable electrode.

Enzyme-amplified redox microarray detection process

Analytical methods and devices are disclosed for separating low abundance analytes by electrophoretically driving the analytes through a sieving matrix to first remove high molecular weight species. Subsequently the remaining low abundance analytes are electrophoretically focused onto a capture membrane where the analytes become bound within a small capture site. After this step the capture membrane may be allowed to dry and then attached to a conductive MALDI sample plate.

Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization(MALDI) mass spectrometry (MS)

Growing community of inventors

Monroe, WA, United States of America

Kilian Dill