Orchid Research Laboratories Limited

Orchid Chemicals & Pharmaceuticals Limited

Orchid Pharma Ltd.

Kilambi Narsimhan

Sriram K Rajagopal

Ravikumar Tadiparthi

Gaddam Om Reddy

Virendra Kachhadia

Venkatesan Parameswaran

Sukunath Narayanan

Uma Ramachandran

Ganapavarapu Veera Raghava Sharma

Sathya Narayana Thara

Venkatesan Janarthanam

Maruthikumar Narayanam

Sathyanarayana Gadde

Akella Satya Surya Visweswara Srinivas

Durairaj Peter Bhakiaraj

Sappanimuthu Thirunavukkarasu

Ganapavarapu Veera Sharma

Visweswara Akella Srinivas

Visweswara Akella Staya Surya Srinivas

Sriram Rajagopal

Gaddam Om Reedy

Novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof are described. These compounds are useful in the treatment of immunological diseases, inflammation, pain disorder, rheumatoid arthritis; osteoporosis; multiple myeloma; uveititis; acute and chronic myelogenous leukemia; atherosclerosis; cancer; cachexia; ischemic-induced cell-damage; pancreatic beta cell destruction; osteoarthritis; rheumatoid spondylitis; gouty arthritis; inflammatory bowel disease; adult respiratory distress syndrome (ARDS); psoriasis; Crohn's disease; allergic rhinitis; ulcerative colitis; anaphylaxis; contact dermatitis; muscle degeneration; asthma; COPD; bone resorption diseases; multiple sclerosis; sepsis; septic shock; toxic shock syndrome and fever. More particularly these compounds are useful as PDE4 inhibitors, and useful for treating PDE4 mediated diseases. 

Heterocycles

Growing community of inventors

Chennai, India

Kilambi Narsimhan